Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS038834-03
Application #
6474977
Study Section
Special Emphasis Panel (ZRG1-AARR-5 (01))
Program Officer
Kerza-Kwiatecki, a P
Project Start
1999-05-01
Project End
2002-04-30
Budget Start
2000-12-01
Budget End
2001-04-30
Support Year
3
Fiscal Year
2000
Total Cost
$313,226
Indirect Cost
Name
Brookhaven National Laboratory
Department
Type
DUNS #
027579460
City
Upton
State
NY
Country
United States
Zip Code
11973
Schifitto, Giovanni; Navia, Bradford A; Yiannoutsos, Constantin T et al. (2007) Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. AIDS 21:1877-86
Schifitto, Giovanni; Yiannoutsos, Constantin T; Simpson, David M et al. (2006) A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy. J Neurovirol 12:328-31
Chang, Linda; Ernst, Thomas; Speck, Oliver et al. (2005) Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. Am J Psychiatry 162:361-9
Chang, Linda; Ernst, Thomas; St Hillaire, Coryse et al. (2004) Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients. Antivir Ther 9:431-40
Cloak, C C; Chang, L; Ernst, T (2004) Increased frontal white matter diffusion is associated with glial metabolites and psychomotor slowing in HIV. J Neuroimmunol 157:147-52
Ernst, Thomas; Chang, Linda (2004) Effect of aging on brain metabolism in antiretroviral-naive HIV patients. AIDS 18 Suppl 1:S61-7
Yiannoutsos, Constantin T; Ernst, Thomas; Chang, Linda et al. (2004) Regional patterns of brain metabolites in AIDS dementia complex. Neuroimage 23:928-35
Zhong, Kai; Ernst, Thomas (2004) Localized in vivo human 1H MRS at very short echo times. Magn Reson Med 52:898-901
Ernst, T; Chang, L; Arnold, S (2003) Increased glial metabolites predict increased working memory network activation in HIV brain injury. Neuroimage 19:1686-93
Chang, Linda; Ernst, Thomas; Witt, Mallory D et al. (2003) Persistent brain abnormalities in antiretroviral-naive HIV patients 3 months after HAART. Antivir Ther 8:17-26

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