Reactive nitrogen species in hypoxic fetal brain injury

Tan, Sidhartha

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS043285-02
• Application #: 6684127
• Study Section: Special Emphasis Panel (ZRG1-BDCN-3 (01))
• Program Officer: Pancrazio, Joseph J
• Project Start: 2002-12-01
• Project End: 2007-11-30
• Budget Start: 2003-12-01
• Budget End: 2004-11-30
• Support Year: 2
• Fiscal Year: 2004
• Total Cost: $413,492

Institution

• Name: Northshore University Healthsystem Research Institute
• DUNS #: 154538107
• City: Evanston
• State: IL
• Country: United States
• Zip Code: 60201

Publications

Drobyshevsky, Alexander; Takada, Silvia Honda; Luo, Kehuan et al. (2015) Elevated spinal monoamine neurotransmitters after antenatal hypoxia-ischemia in rabbit cerebral palsy model. J Neurochem 132:394-402

Drobyshevsky, Alexander; Cotten, C Michael; Shi, Zhongjie et al. (2015) Human Umbilical Cord Blood Cells Ameliorate Motor Deficits in Rabbits in a Cerebral Palsy Model. Dev Neurosci 37:349-62

Drobyshevsky, Alexander; Jiang, Rugang; Derrick, Matthew et al. (2014) Functional correlates of central white matter maturation in perinatal period in rabbits. Exp Neurol 261:76-86

Drobyshevsky, Alexander; Jiang, Rugang; Lin, Laixiang et al. (2014) Unmyelinated axon loss with postnatal hypertonia after fetal hypoxia. Ann Neurol 75:533-41

Yu, Lei; Vásquez-Vivar, Jeannette; Jiang, Rugang et al. (2014) Developmental susceptibility of neurons to transient tetrahydrobiopterin insufficiency and antenatal hypoxia-ischemia in fetal rabbits. Free Radic Biol Med 67:426-36

Drobyshevsky, Alexander; Derrick, Matthew; Luo, Kehuan et al. (2012) Near-term fetal hypoxia-ischemia in rabbits: MRI can predict muscle tone abnormalities and deep brain injury. Stroke 43:2757-63

Derrick, Matthew; Englof, Ila; Drobyshevsky, Alexander et al. (2012) Intrauterine fetal demise can be remote from the inciting insult in an animal model of hypoxia-ischemia. Pediatr Res 72:154-60

Drobyshevsky, Alexander; Luo, Kehuan; Derrick, Matthew et al. (2012) Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants. J Neurosci 32:5500-9

Yu, Lei; Derrick, Matthew; Ji, Haitao et al. (2011) Neuronal nitric oxide synthase inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: comparison between JI-8 and 7-nitroindazole. Dev Neurosci 33:312-9

Rao, Suma; Lin, Zhenlang; Drobyshevsky, Alexander et al. (2011) Involvement of neuronal nitric oxide synthase in ongoing fetal brain injury following near-term rabbit hypoxia-ischemia. Dev Neurosci 33:288-98