Agency
National Institute of Health (NIH)
Institute
National Institute for Occupational Safety and Health (NIOSH)
Type
Research Project (R01)
Project #
3R01OH008531-03S1
Application #
7422526
Study Section
Safety and Occupational Health Study Section (SOH)
Program Officer
Frederick, Linda J
Project Start
2006-09-01
Project End
2010-07-31
Budget Start
2006-09-01
Budget End
2007-07-31
Support Year
3
Fiscal Year
2005
Total Cost
$32,234
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Zhu, Jian-Hong; Chen, Chun-Lin; Flavahan, Sheila et al. (2011) Cyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3. Am J Physiol Heart Circ Physiol 300:H1770-80
Goel, Aditya; Su, Baogen; Flavahan, Sheila et al. (2010) Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries. Circ Res 107:242-51
Crassous, P A; Flavahan, S; Flavahan, N A (2009) Acute dilation to alpha(2)-adrenoceptor antagonists uncovers dual constriction and dilation mediated by arterial alpha(2)-adrenoceptors. Br J Pharmacol 158:1344-55
Hughes, Jennifer M; Wirth, Oliver; Krajnak, Kristine et al. (2009) Increased oxidant activity mediates vascular dysfunction in vibration injury. J Pharmacol Exp Ther 328:223-30
Flavahan, Nicholas A (2008) Regulation of vascular reactivity in scleroderma: new insights into Raynaud's phenomenon. Rheum Dis Clin North Am 34:81-7;vii
Eid, A H; Chotani, M A; Mitra, S et al. (2008) Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors. Am J Physiol Heart Circ Physiol 295:H266-72
Eid, A H; Maiti, K; Mitra, S et al. (2007) Estrogen increases smooth muscle expression of alpha2C-adrenoceptors and cold-induced constriction of cutaneous arteries. Am J Physiol Heart Circ Physiol 293:H1955-61
Krajnak, K; Dong, R G; Flavahan, S et al. (2006) Acute vibration increases alpha2C-adrenergic smooth muscle constriction and alters thermosensitivity of cutaneous arteries. J Appl Physiol 100:1230-7
Flavahan, Nicholas A (2006) A farewell kiss triggers a broken heart? Circ Res 98:1117-9