Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Project (R01)
Project #
5R01RR010742-05
Application #
2286315
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1989-04-01
Project End
1997-03-31
Budget Start
1995-09-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Brun, Yseult Francoise; Greco, William R (2010) Characterization of a three-drug nonlinear mixture response model. Front Biosci (Schol Ed) 2:454-67
Khinkis, Leonid A; Krzyzanski, Wojciech; Jusko, William J et al. (2009) D-optimal designs for parameter estimation for indirect pharmacodynamic response models. J Pharmacokinet Pharmacodyn 36:523-39
Brun, Yseult F; Varma, Ram; Hector, Suzanne M et al. (2008) Simultaneous modeling of concentration-effect and time-course patterns in gene expression data from microarrays. Cancer Genomics Proteomics 5:43-53
Brun, Yseult F; Dennis, Carly G; Greco, William R et al. (2007) Modeling the combination of amphotericin B, micafungin, and nikkomycin Z against Aspergillus fumigatus in vitro using a novel response surface paradigm. Antimicrob Agents Chemother 51:1804-12
Varma, Ram; Hector, Suzanne; Greco, William R et al. (2007) Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells. Cancer Chemother Pharmacol 59:711-23
Kau, Yi-Chuan; Hung, Yu-Chun; Zizza, Anthony M et al. (2006) Efficacy of lidocaine or bupivacaine combined with ephedrine in rat sciatic nerve block. Reg Anesth Pain Med 31:14-8
Varma, Rama R; Hector, Suzanne M; Clark, Kimberly et al. (2005) Gene expression profiling of a clonal isolate of oxaliplatin-resistant ovarian carcinoma cell line A2780/C10. Oncol Rep 14:925-32
Faessel, Helene M; Slocum, Harry K; Rustum, Youcef M et al. (2003) Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells. Int J Oncol 23:401-9
White, Donald B; Slocum, Harry K; Brun, Yseult et al. (2003) A new nonlinear mixture response surface paradigm for the study of synergism: a three drug example. Curr Drug Metab 4:399-409
Slocum, H K; Parsons, J C; Winslow, E O et al. (2000) Time-lapse video reveals immediate heterogeneity and heritable damage among human ileocecal carcinoma HCT-8 cells treated with raltitrexed (ZD1694). Cytometry 41:252-60

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