The proposed research will examine how health and nutrition (as well other social and demographic factors) affect educational attainment, work patterns and wages of young adults in Cebu, Philippines. We will use existing data from our ongoing Cebu Longitudinal Health and Nutrition Survey, augmented by new data from two additional survey rounds. We will develop and estimate comprehensive longitudinal models of adult wages and prior school achievement that account for the cumulative and age-specific effects of individual, household and community factors. Central among the determinants is a vector of factors representing multiple aspects of child health at different ages, including birth characteristics, diet and nutritional status, infectious disease morbidity, preventive health care, early child growth, cognitive ability, and psychological well being. These will be considered in the context of household socioeconomic factors (e.g., parental education, household composition, income and assets) and community characteristics. Specifically, we will (1) estimate the effects of early childhood and concurrent health and nutrition on multiple aspects of schooling, including age at entry into primary school, grade repetition, grade completion through secondary school, and achievement measured with standard tests; (2) estimate the effects of health history from birth to adulthood on work and earnings; and (3) explore the possibility there are distinct pathways through which nutrition and health affect economic outcomes. The """"""""brains"""""""" pathway traces the effects of early childhood health and nutrition on cognitive and behavioral development, through school achievement and educational attainment to wages. We hypothesize that this pathway will be important in a rapidly developing economy, where there is a growing emphasis on jobs requiring intellectual skills. The """"""""brawn"""""""" pathway follows the effects of childhood health and nutrition on physical development, which is likely to affect work capacity (and thus wages) in physically demanding jobs. We will also explore the extent to which there are direct effects of health on economic outcomes. Our longitudinal modeling strategy accounts for biases related to different aspects of sample selectivity, the endogeneity of child health and other inputs such as schooling when estimating wages, omitted variables and measurement error.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
Research Project (R01)
Project #
1R01TW005596-01
Application #
6346594
Study Section
Special Emphasis Panel (ZRG1-SNEM-3 (02))
Program Officer
Rosenthal, Joshua
Project Start
2001-05-05
Project End
2006-04-30
Budget Start
2001-05-05
Budget End
2002-04-30
Support Year
1
Fiscal Year
2001
Total Cost
$353,436
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Miscellaneous
Type
Schools of Public Health
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Chiong, Charlotte M; Reyes-Quintos, Ma Rina T; Yarza, Talitha Karisse L et al. (2018) The SLC26A4 c.706C>G (p.Leu236Val) Variant is a Frequent Cause of Hearing Impairment in Filipino Cochlear Implantees. Otol Neurotol 39:e726-e730
Tennyson, Robert L; Gettler, Lee T; Kuzawa, Christopher W et al. (2018) Lifetime socioeconomic status and early life microbial environments predict adult blood telomere length in the Philippines. Am J Hum Biol 30:e23145
Bethancourt, Hilary J; Kratz, Mario; Beresford, Shirley A A et al. (2017) No association between blood telomere length and longitudinally assessed diet or adiposity in a young adult Filipino population. Eur J Nutr 56:295-308
Justice, Anne E (see original citation for additional authors) (2017) Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun 8:14977
Spracklen, Cassandra N; Chen, Peng; Kim, Young Jin et al. (2017) Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum Mol Genet 26:1770-1784
Eisenberg, Dan T A; Borja, Judith B; Hayes, M Geoffrey et al. (2017) Early life infection, but not breastfeeding, predicts adult blood telomere lengths in the Philippines. Am J Hum Biol 29:
Ryan, Calen P; McDade, Thomas W; Gettler, Lee T et al. (2017) Androgen receptor CAG repeat polymorphism and hypothalamic-pituitary-gonadal function in Filipino young adult males. Am J Hum Biol 29:
McDade, Thomas W; Ryan, Calen; Jones, Meaghan J et al. (2017) Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood. Proc Natl Acad Sci U S A 114:7611-7616
Wen, Wanqing; Kato, Norihiro; Hwang, Joo-Yeon et al. (2016) Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Sci Rep 6:17958
Ehret, Georg B (see original citation for additional authors) (2016) The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet 48:1171-1184

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