This proposal is based on correlated evidence between plasma levels of cytokine and the development of side effects in patients undergoing irradiation. Based on the above, this protocol will take patients entered into two RTOG protocols and establish a database on plasma and cytokine levels in these patients.
The aims are to define the changes in the levels of cytokine(s) present in the plasma and urine of patients undergoing XRT +/-endocrine therapy and to correlate levels with the development of acute and late side effects.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Research Grants (R03)
Project #
5R03CA075948-02
Application #
2733404
Study Section
Special Emphasis Panel (ZCA1-GRB-Z (M2))
Program Officer
Stone, Helen B
Project Start
1997-07-07
Project End
2001-06-30
Budget Start
1998-07-01
Budget End
2001-06-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
East Carolina University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
City
Greenville
State
NC
Country
United States
Zip Code
27858