This is an initial submission in response to program announcement PAR-01-056. The Principal investigator (David Sarwer, Ph.D.) is currently in the third year of a K23 Mentored Patient-Oriented Research Career Development Award (K23-DK60023) from NIDDK. One of the studies supported by that award is an investigation of the psychosocial status of bariatric surgery patients. The proposed Study in this application builds upon preliminary findings from that study and is designed to generate pilot data for a subsequent R01 application. Presently, 6.3 % of women and 3.1% of men suffer from extreme obesity, defined as a body mass index (BMI) >= 40 kg/m 2. For many of these individuals, bariatric surgery is the most efficacious intervention. Patients typically lose 40-60% of their excess body weight and frequently experience improvements in obesity-related co-morbidities. Surprisingly, there have been few studies of postoperative eating behavior and its relationship to weight loss, as well as of untoward events such as nausea, vomiting, and dumping. Several studies, including preliminary data from our ongoing investigation, have suggested that patients who adhere poorly to the postoperative diet experience smaller weight losses. The present study will investigate weight loss, caloric and macronutrient intake, eating behavior, nausea, vomiting, and dumping in 100 patients who undergo bariatric surgery. Fifty individuals will receive biweekly dietary counseling for the first 16 postoperative weeks. Fifty will receive standard post-operative care, which involves no postoperative dietary counseling but access to a monthly support group and on-line chat room. We predict that at 4, 6, 12, and 18 months postoperatively patients who receive intensive dietary counseling will experience larger weight losses and better dietary adherence, as well as less frequent nausea, vomiting, and dumping, as compared to those who receive standard care. The inclusion of dietary counseling during the postoperative period is an innovation in the treatment of bariatric surgery patients. Results of this study could have a significant impact on the postoperative care of these individuals.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Small Research Grants (R03)
Project #
1R03DK067885-01
Application #
6806802
Study Section
Special Emphasis Panel (ZDK1-GRB-8 (M1))
Program Officer
Kuczmarski, Robert J
Project Start
2004-09-01
Project End
2006-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
1
Fiscal Year
2004
Total Cost
$158,500
Indirect Cost
Name
University of Pennsylvania
Department
Psychiatry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sarwer, David B; Moore, Renee H; Spitzer, Jacqueline C et al. (2012) A pilot study investigating the efficacy of postoperative dietary counseling to improve outcomes after bariatric surgery. Surg Obes Relat Dis 8:561-8
Sarwer, David B; Dilks, Rebecca J; West-Smith, Lisa (2011) Dietary intake and eating behavior after bariatric surgery: threats to weight loss maintenance and strategies for success. Surg Obes Relat Dis 7:644-51
Thomas, J Graham; Bond, Dale S; Sarwer, David B et al. (2011) Technology for behavioral assessment and intervention in bariatric surgery. Surg Obes Relat Dis 7:548-57
Sarwer, David B; Wadden, Thomas A; Moore, Renee H et al. (2008) Preoperative eating behavior, postoperative dietary adherence, and weight loss after gastric bypass surgery. Surg Obes Relat Dis 4:640-6
Sarwer, David B; Fabricatore, Anthony N (2008) Psychiatric considerations of the massive weight loss patient. Clin Plast Surg 35:1-10
Sarwer, David B; Thompson, J Kevin; Mitchell, James E et al. (2008) Psychological considerations of the bariatric surgery patient undergoing body contouring surgery. Plast Reconstr Surg 121:423e-434e
Crerand, Canice E; Infield, Alison L; Sarwer, David B (2007) Psychological considerations in cosmetic breast augmentation. Plast Surg Nurs 27:146-54
Sarwer, David B (2007) The psychological aspects of cosmetic breast augmentation. Plast Reconstr Surg 120:110S-117S
Sarwer, David B; Brown, Gregory K; Evans, Dwight L (2007) Cosmetic breast augmentation and suicide. Am J Psychiatry 164:1006-13
Fabricatore, Anthony N; Crerand, Canice E; Wadden, Thomas A et al. (2006) How do mental health professionals evaluate candidates for bariatric surgery? Survey results. Obes Surg 16:567-73

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