Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Research Grants (R03)
Project #
5R03EY014427-02
Application #
6688229
Study Section
Special Emphasis Panel (ZEY1-VSN (01))
Program Officer
Mariani, Andrew P
Project Start
2003-01-01
Project End
2005-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$146,500
Indirect Cost
Name
University of Oklahoma Health Sciences Center
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
878648294
City
Oklahoma City
State
OK
Country
United States
Zip Code
73117
Kong, Li; Zhou, Xiaohong; Li, Feng et al. (2010) Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice. Neurobiol Dis 38:446-55
Zhou, Xiaohong; Li, Feng; Kong, Li et al. (2009) Anti-inflammatory effect of pigment epithelium-derived factor in DBA/2J mice. Mol Vis 15:438-50
Wang, Joshua J; Zhang, Sarah X; Mott, Robert et al. (2006) Salutary effect of pigment epithelium-derived factor in diabetic nephropathy: evidence for antifibrogenic activities. Diabetes 55:1678-85
Li, Chao; Tang, Yuhong; Li, Feng et al. (2006) 17beta-estradiol (betaE2) protects human retinal Muller cell against oxidative stress in vitro: evaluation of its effects on gene expression by cDNA microarray. Glia 53:392-400
Kong, Li; Li, Feng; Soleman, Charles E et al. (2006) Bright cyclic light accelerates photoreceptor cell degeneration in tubby mice. Neurobiol Dis 21:468-77
Zhou, Xiaohong; Li, Feng; Kong, Li et al. (2005) Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma. J Biol Chem 280:31240-8
Yu, Xiaorui; Tang, Yuhong; Li, Feng et al. (2005) Protection against hydrogen peroxide-induced cell death in cultured human retinal pigment epithelial cells by 17beta-estradiol: a differential gene expression profile. Mech Ageing Dev 126:1135-45
Yu, Xiaorui; Rajala, Raju V S; McGinnis, James F et al. (2004) Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 beta-estradiol-mediated neuroprotection. J Biol Chem 279:13086-94
Yan, Xin; Shen, Hua; Zaharia, Marian et al. (2004) Involvement of phosphatidylinositol 3-kinase and insulin-like growth factor-I in YXLST-mediated neuroprotection. Brain Res 1006:198-206
Cao, Wei; Rajala, Raju V S; Li, Feng et al. (2003) Neuroprotective effect of estrogen upon retinal neurons in vitro. Adv Exp Med Biol 533:395-402