Despite tremendous progress in psychology and neuroscience, physical therapists treating patients with stroke still rely on unspecific guidelines to determine task practice schedules for functional motor skill reacquisition. The present proposal is novel in defining specific rehabilitation practice protocols derived from psychological learning theory, with particular emphasis on the """"""""micro-scheduling"""""""" of the practice trials to enhance learning. Previous research in word-learning and motor skill learning shows that practice schedules 1) in which the task presentations are variable, or 2) in which the intervals between presentations of individual tasks are expanded, significantly enhance long-term retention and generalization of learning. In this pilot study, the PIs use a manual grasping task, and propose to demonstrate with participants who are recovering from stroke-hemiparesis that massed, random, and expanded variable practice schedules affect differentially the acquisition performance and the learning of motor skills. Further, using a stratified experimental design, they aim to show an interaction between practice schedule and impairment severity such that the best practice schedule depends on stroke severity. The hypothesis is that subjects with mild deficits benefit most from expanded variable practice, whereas subjects with moderate deficits benefit most from massed practice schedules. ? ?
| Han, Cheol E; Kim, Sujin; Chen, Shuya et al. (2013) Quantifying arm nonuse in individuals poststroke. Neurorehabil Neural Repair 27:439-47 |
| Schweighofer, Nicolas; Choi, Younggeun; Winstein, Carolee et al. (2012) Task-oriented rehabilitation robotics. Am J Phys Med Rehabil 91:S270-9 |
| Hidaka, Yukikazu; Han, Cheol E; Wolf, Steven L et al. (2012) Use it and improve it or lose it: interactions between arm function and use in humans post-stroke. PLoS Comput Biol 8:e1002343 |
| Schweighofer, Nicolas; Lee, Jeong-Yoon; Goh, Hui-Ting et al. (2011) Mechanisms of the contextual interference effect in individuals poststroke. J Neurophysiol 106:2632-41 |
| Choi, Younggeun; Gordon, James; Park, Hyeshin et al. (2011) Feasibility of the adaptive and automatic presentation of tasks (ADAPT) system for rehabilitation of upper extremity function post-stroke. J Neuroeng Rehabil 8:42 |
| Lee, Jeong-Yoon; Schweighofer, Nicolas (2009) Dual adaptation supports a parallel architecture of motor memory. J Neurosci 29:10396-404 |
| Choi, Younggeun; Qi, Feng; Gordon, James et al. (2008) Performance-based adaptive schedules enhance motor learning. J Mot Behav 40:273-80 |
