The proposed secondary analysis of data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (SECCYD) will focus on assessing the role of chronic illness, such as asthma, on the emotional, developmental, and behavioral health of children. Sophisticated data analysis techniques will be used to model the development of chronic illnesses over time, while at the same time trends of developmental health will be modeled from the longitudinal data. Taking into account the confounding effect of various demographic, socioeconomic, and child care factors, the impact of chronic illness on the observed trends of emotional, developmental, and behavioral health over time will then be assessed. The complications involved with simultaneous modeling of both chronic illness as well as developmental health measures over time will require further advances of statistical methodologies to best address this proposed aim of the study. ? ? ?
| Gurka, Matthew J; Edwards, Lloyd J; Muller, Keith E (2011) Avoiding bias in mixed model inference for fixed effects. Stat Med 30:2696-707 |
| Gurka, Matthew J; LoCasale-Crouch, Jennifer; Blackman, James A (2010) Long-term cognition, achievement, socioemotional, and behavioral development of healthy late-preterm infants. Arch Pediatr Adolesc Med 164:525-32 |
| Gurka, Matthew J; Blackman, James A; Heymann, Peter W (2009) Risk of childhood asthma in relation to the timing of early child care exposures. J Pediatr 155:781-787.e1 |
