This is a proposal to extend the analysis of the carotid ultrasound data collected during the Asymptomatic Carotid Artery Progression Study (ACAPS), a double-masked, placebo-controlled randomized clinical trial of 919 high risk men and women, to observe the contour of the intimal medial thickening (IMT) changes that occurred from baseline through three years of follow up, taking advantage of the multiple measurements taken from multiple sites in the original study.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Research Grants (R03)
Project #
1R03HL054533-01
Application #
2232900
Study Section
Clinical Trials Review Committee (CLTR)
Project Start
1995-09-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1996-08-31
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Espeland, M A; Craven, T E; Miller, M E et al. (1999) 1996 Remington lecture: modeling multivariate longitudinal data that are incomplete. Ann Epidemiol 9:196-205