The long-term objectives of this project are to increase the yield of developmentally-competent oocytes from rhesus monkey. The information acquired in the proposed studies should be useful with respect to in vitro maturation of human oocytes and oocytes from endangered animals, as well as to the basic scientific understanding of the process involved in normal oocyte development. The two specific aims of the project are (1) to determine optimal culture conditions (energy, substrates, nutrients and vitamins) for supporting acquisition of developmental competence during oocyte maturation in vitro, and (2) to determine if maintaining meiotic arrest for several days during culture of germinal vesicle stage oocytes enhances their subsequent developmental competence.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
Small Research Grants (R03)
Project #
5R03TW000840-03
Application #
2910798
Study Section
International and Cooperative Projects 1 Study Section (ICP)
Program Officer
Michels, Kathleen M
Project Start
1997-05-01
Project End
2000-08-31
Budget Start
1999-05-01
Budget End
2000-08-31
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715