Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21AI044304-01A1
Application #
2875913
Study Section
Special Emphasis Panel (ZRG1-AARR-2 (01))
Program Officer
Bende, Steve M
Project Start
1999-06-01
Project End
2001-05-31
Budget Start
1999-06-01
Budget End
2000-05-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Wistar Institute
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Chehimi, Jihed; Campbell, Donald E; Azzoni, Livio et al. (2002) Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals. J Immunol 168:4796-801
Weissman, Drew; Montaner, Luis J (2002) Immune reconstitution. Clin Lab Med 22:719-40
Azzoni, Livio; Papasavvas, Emmanouil; Chehimi, Jihed et al. (2002) Sustained impairment of IFN-gamma secretion in suppressed HIV-infected patients despite mature NK cell recovery: evidence for a defective reconstitution of innate immunity. J Immunol 168:5764-70
Moonis, M; Lee, B; Bailer, R T et al. (2001) CCR5 and CXCR4 expression correlated with X4 and R5 HIV-1 infection yet not sustained replication in Th1 and Th2 cells. AIDS 15:1941-9
Ma, X; Sun, J; Papasavvas, E et al. (2000) Inhibition of IL-12 production in human monocyte-derived macrophages by TNF. J Immunol 164:1722-9
Lee, B; Montaner, L J (1999) Chemokine immunobiology in HIV-1 pathogenesis. J Leukoc Biol 65:552-65
Lee, B; Sharron, M; Montaner, L J et al. (1999) Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A 96:5215-20
Montaner, L J; da Silva, R P; Sun, J et al. (1999) Type 1 and type 2 cytokine regulation of macrophage endocytosis: differential activation by IL-4/IL-13 as opposed to IFN-gamma or IL-10. J Immunol 162:4606-13