The HIV epidemic is accelerating among young men who have sex with men (YMSM, 18 to 24 years) in Bangkok where HIV incidence was reported to be 8.8 to 12.2 per 100 person-years, the highest such incidence documented in Asia. Engagement and retention of YMSM of unknown or HIV negative serostatus in regular (at least annual) HIV testing is essential for timely linkage to HIV prevention services, such as risk reduction counseling and HIV chemoprophylaxis. Among YMSM unaware of an existing or new HIV infection, timely identification is necessary to increase linkage and initiation of antiretrovial treatment and care to improve disease outlook and prevent onward HIV transmission. However, structural, logistical and psychosocial barriers limit the uptake and retention of Thai MSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services targeting this population. This study proposes the use of online HIV testing (OHT) as an alternative HIV testing modality to increase engagement, retention and linkage of YMSM in HIV prevention, treatment and care services.
The specific aims of this research proposal are 1) To qualitatively explore barriers and facilitators to OHT among Bangkok YMSM; 2) To quantitatively examine current perceptions, barriers, facilitators to HIV testing among Bangkok YMSM and estimate the proportion likely to undergo OHT, identify factors associated with willingness to access OHT and to participate in a pilot study of this new HIV testing modality; and 3) To determine the acceptability and feasibility of OHT using a new HIV rapid diagnostic antibody/antigen-based self-test in real time and a self-collected dried blood spot (DBS) with centralized HIV DNA testing. Results of rapid testing will be read- and of centralized testing will be delivered by video conference, followed by discussion, post-test counseling and linkage to care and treatment, in a 6-month pilot study. Particularly, logistical issues, concerns over rapid HIV self-testing, DBS self-collection and laboratory testing, reading or reporting of results by video conferencing will be assessed, as well as how OHT may help to overcome some of the existing barriers to HIV testing. Using new HIV diagnostic and online technologies, OHT may be a promising strategy to increase engagement, retention and linkage to HIV prevention, treatment and care services among Thai YMSM.

Public Health Relevance

The HIV epidemic in Thailand is accelerating among young men who have sex with men (YMSM, 18 to 24 years). However, structural, logistical and psychosocial barriers limit the uptake and retention of Bangkok YMSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services. This exploratory and feasibility study proposes the use of online HIV testing, using a new HIV rapid diagnostic Ag/Ab combo-based self-test in real time and a self-collected dried blood spot with centralized HIV DNA testing as an alternative HIV testing modality to increase the linkage of YMSM to HIV prevention and care continuum.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21AI120816-01A1
Application #
9064254
Study Section
Behavioral and Social Science Approaches to Preventing HIV/AIDS Study Section (BSPH)
Program Officer
Sharp, Gerald B
Project Start
2016-02-08
Project End
2018-01-31
Budget Start
2016-02-08
Budget End
2017-01-31
Support Year
1
Fiscal Year
2016
Total Cost
$138,279
Indirect Cost
$9,987
Name
Mahidol University
Department
Type
DUNS #
660984043
City
Nakhon Pathom
State
Country
Thailand
Zip Code
73170
van Griensven, Frits; Guadamuz, Thomas E; de Lind van Wijngaarden, Jan Willem et al. (2017) Challenges and emerging opportunities for the HIV prevention, treatment and care cascade in men who have sex with men in Asia Pacific. Sex Transm Infect 93:356-362