Overall Objective: The overall aim of this study is to develop and test a theory-based guided imagery lifestyle intervention to reduce risk factors for type 2 diabetes and cardiovascular disease in overweight Latino adolescents. Overall Hypothesis: Guided imagery lifestyle intervention will be more effective than nutrition education alone in decreasing risk factors for type 2 diabetes and cardiovascular disease, and in increasing health-promoting dietary and physical activity behaviors.
Specific Aims and Approach:
Specific Aim 1 : To develop a guided imagery intervention program based on stress reduction and on the Theory of Meanings of Behavior for use with overweight Latino adolescents.
Specific Aim 2 : To conduct a randomized and controlled trial to test the direct and mediated effects of adding a guided imagery intervention program to a nutrition education program in overweight Latino adolescents. Major outcomes will include insulin sensitivity, psychosocial measures, and dietary and physical activity behaviors. Rationale: Prevalence of obesity and type 2 diabetes is increasing in overweight youth, especially in ethnic minorities. 28% of overweight Latino adolescents with a family history of type 2 diabetes have impaired glucose tolerance (IGT), and 30% have the metabolic syndrome. There is a critical need to develop innovative and effective lifestyle interventions to reduce insulin resistance and overweight in this population at risk. Research Design & Methods: Using focus group qualitative methods, a 12-week guided imagery intervention program will be developed that is culturally and developmentally appropriate for overweight Latino adolescents. This intervention will then be tested in a randomized, controlled trial. Outcome assessments will include physiologic measures (insulin sensitivity, body composition, cortisol secretion), psychosocial measures (perceived stress, emotional eating, meanings of eating and physical activity), and behavioral measures (dietary intake and physical activity). Health implications: Guided imagery holds particular promise to reduce chronic disease risk factors in overweight adolescents by reducing chronic stress and transforming unhealthful dietary and physical activity behaviors. This could be an effective means of preventing both type 2 diabetes and cardiovascular disease in susceptible youth, thereby reducing both the suffering and costs associated with these diseases. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21AT002556-02
Application #
7296130
Study Section
Special Emphasis Panel (ZAT1-JH (13))
Program Officer
Duffy, Linda C
Project Start
2006-09-30
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2009-08-31
Support Year
2
Fiscal Year
2007
Total Cost
$356,114
Indirect Cost
Name
University of Southern California
Department
Pediatrics
Type
Schools of Medicine
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Hsieh, Stephanie; Klassen, Ann C; Curriero, Frank C et al. (2015) Built Environment Associations with Adiposity Parameters among Overweight and Obese Hispanic Youth. Prev Med Rep 2:406-412
Hsieh, Stephanie; Klassen, Ann C; Curriero, Frank C et al. (2014) Fast-food restaurants, park access, and insulin resistance among Hispanic youth. Am J Prev Med 46:378-87
Weigensberg, Marc J; Lane, Christianne J; Ávila, Quintilia et al. (2014) Imagine HEALTH: results from a randomized pilot lifestyle intervention for obese Latino adolescents using Interactive Guided ImagerySM. BMC Complement Altern Med 14:28
Weigensberg, Marc J; Lane, Christianne Joy; Winners, Oscar et al. (2009) Acute effects of stress-reduction Interactive Guided Imagery(SM) on salivary cortisol in overweight Latino adolescents. J Altern Complement Med 15:297-303