Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21CA064137-01A2
Application #
2106419
Study Section
Pathology B Study Section (PTHB)
Project Start
1996-03-03
Project End
1998-03-02
Budget Start
1996-03-03
Budget End
1997-03-02
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Anatomy/Cell Biology
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Jean, D; Bar-Eli, M (2000) Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor family. Mol Cell Biochem 212:19-28
Huang, S; Ullrich, S E; Bar-Eli, M (1999) Regulation of tumor growth and metastasis by interleukin-10: the melanoma experience. J Interferon Cytokine Res 19:697-703
Bar-Eli, M (1999) Role of interleukin-8 in tumor growth and metastasis of human melanoma. Pathobiology 67:12-8
Luca, M R; Bar-Eli, M (1998) Molecular changes in human melanoma metastasis. Histol Histopathol 13:1225-31
Frade, R; Rodrigues-Lima, F; Huang, S et al. (1998) Procathepsin-L, a proteinase that cleaves human C3 (the third component of complement), confers high tumorigenic and metastatic properties to human melanoma cells. Cancer Res 58:2733-6
Jean, D; Gershenwald, J E; Huang, S et al. (1998) Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells. J Biol Chem 273:16501-8
Jean, D; Harbison, M; McConkey, D J et al. (1998) CREB and its associated proteins act as survival factors for human melanoma cells. J Biol Chem 273:24884-90
Huang, S; Jean, D; Luca, M et al. (1998) Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis. EMBO J 17:4358-69
Xie, S; Price, J E; Luca, M et al. (1997) Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells. Oncogene 15:2069-75
Johnson, J P; Bar-Eli, M; Jansen, B et al. (1997) Melanoma progression-associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligand. Int J Cancer 73:769-74

Showing the most recent 10 out of 13 publications