Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21CA069845-02
Application #
2113815
Study Section
Special Emphasis Panel (SRC (06))
Project Start
1995-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Pierson, Christopher R; McGowen, Richard; Grignon, David et al. (2002) Maspin is up-regulated in premalignant prostate epithelia. Prostate 53:255-62
Reddy, K B; McGowen, R; Schuger, L et al. (2001) Maspin expression inversely correlates with breast tumor progression in MMTV/TGF-alpha transgenic mouse model. Oncogene 20:6538-43
Biliran Jr, H; Sheng, S (2001) Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin. Cancer Res 61:8676-82
McGowen, R; Biliran Jr, H; Sager, R et al. (2000) The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin. Cancer Res 60:4771-8
Chen, Y Q; Hsieh, J T; Yao, F et al. (1999) Induction of apoptosis and G2/M cell cycle arrest by DCC. Oncogene 18:2747-54
Reddy, K B; Keshamouni, V G; Chen, Y Q (1999) The level of tyrosine kinase activity regulates the expression of p21/WAF1 in cancer cells. Int J Oncol 15:301-6
Trikha, M; Cai, Y; Grignon, D et al. (1998) Identification of a novel truncated alphaIIb integrin. Cancer Res 58:4771-5
Chopra, D P; Grignon, D J; Joiakim, A et al. (1996) Differential growth factor responses of epithelial cell cultures derived from normal human prostate, benign prostatic hyperplasia, and primary prostate carcinoma. J Cell Physiol 169:269-80