Chronic pain from a variety of health conditions is very common; for many people suffering disabling conditions, opioid analgesics are a necessary treatment since this class of drugs is among the most powerful treatments for most forms of pain. However, long-term opioid treatment, particularly in the setting of chronic pain, can produce negative health consequences such as opioid tolerance, dependence, withdrawal, and intoxication. This has created a difficult situation for health care providers who are considering using opioids to treat their patients for pain. Furthermore, restrictions placed upon physicians to adequately treat legitimate pain have led some patients to seek pain medications from alternate sources, such as Internet pharmacies. This proposal intends to determine the characteristics of individuals who purchase opioid analgesics from Internet pharmacies to treat chronic pain, as well as to compare differences in opioid knowledge, attitudes, beliefs, and practices among patients with chronic pain. Furthermore, this study will determine the feasibility of conducting a longitudinal study in a population who purchase opioid analgesics from Internet pharmacies. Data from this cross-sectional study will inform treatment efforts directed toward patients with chronic pain. This study also furthers the important goals of the NIH Roadmap by creating new organizational models for behavioral science, arranging online partnerships of research between academic investigators and an organized community of chronic pain patients who congregate only in cyberspace.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21DA022677-02
Application #
7295754
Study Section
Special Emphasis Panel (ZDA1-MXG-S (05))
Program Officer
Denisco, Richard A
Project Start
2006-09-30
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2009-08-31
Support Year
2
Fiscal Year
2007
Total Cost
$149,683
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Emergency Medicine
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Boyer, Edward W (2012) Management of opioid analgesic overdose. N Engl J Med 367:146-55
Boyer, Edward W; Wines Jr, James D (2008) Impact of Internet pharmacy regulation on opioid analgesic availability. J Stud Alcohol Drugs 69:703-8
Boyer, Edward W; Babu, Kavita M; Adkins, Jessica E et al. (2008) Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth). Addiction 103:1048-50
Boyer, Edward W; Babu, Kavita M; Macalino, Grace E et al. (2007) Self-treatment of opioid withdrawal with a dietary supplement, Kratom. Am J Addict 16:352-6