Limitations in detector performance have kept medical radiology from utilizing and enjoying the full benefits of digital technology. The major obstacles have been material performance and lack of viable commercial processes to fabricate large area screens. We propose to develop a new technology for the synthesis of such scintillating screens based on vapor deposition of films, a technology ideally suited to this purpose. Initially we intend to work with a new scintillator material, a Lu2O3 optical ceramic, which has displayed impressive performance in dental x-ray applications. However its utilization and commercialization for medical applications has been impractical because of the way materials and devices are currently fabricated. The two processes that are directly responsible, namely hot pressing (which limits size and shape) and laser pixelation (time-consuming and expensive), will be eliminated by the new technology we propose, resulting in a new breed of .advanced scintillators. We . will begin by utilizing PVD to fabricate exploratory coatings that wilLenable early characterization and evaluation. This will provide valuable information for our primary effort on CVD, which is our process of choice for achieving the thicknesses that will ultimately be heeded. Guided by chemical thermodynamics and kinetics, we will deposit fully dense transparent films of this material in thicknesses >200 jam, and areas up to10 cm2 (limited only by our experimental equipment size). We will further seek to control the microstructure, and use tailored substrates (using photoresist techniques) so as to enhance channeling of the emitted light toward the photodetectorand to minimize laterial scattering. The success of this research will advance the performance of systems for digital radiology beyond that of conventional film-screen technology and make possible the widespread replacement of the latter for general radiological applications. This will for the first time make the benefits of digital techniques in data management, image enhancement, and differential analysis widely available to the broad medical radiological community. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21EB005037-02
Application #
7230237
Study Section
Biomedical Imaging Technology Study Section (BMIT)
Program Officer
Lopez, Hector
Project Start
2006-05-01
Project End
2010-04-30
Budget Start
2007-05-01
Budget End
2010-04-30
Support Year
2
Fiscal Year
2007
Total Cost
$197,142
Indirect Cost
Name
Boston University
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
049435266
City
Boston
State
MA
Country
United States
Zip Code
02215
Topping, Stephen G; Sarin, V K (2009) CVD Lu(2)O(3):Eu coatings For Advanced Scintillators. Int J Refract Metals Hard Mater 27:498-501
Topping, Stephen G; Park, Ch; Rangan, Sk et al. (2007) Lutetium Oxide Coatings by PVD. Mater Res Soc Symp Proc 1038:115-120