This National Eye Institiute Clinical Research Development Award enhances and further develops clinical vision research at the newly dedicated David M. Worthen Center for Clinical Studies. The Worthen Center is a 2,000 square foot clinical research facility at the Center for Sight, Georgetown University Medical Center, Washington, D.C. The award provides the Worthen Center staff with substantial capability in the biostatistical, epidemiological, and clinical research methodology necessary to conduct single-center studies, and to design, plan, implement, and lead multi-center randomized clinical trials and other epidemiologic investigations. The Center for Sight already conducts an extensive array of local clinical research projects, primarily in the areas of corneal disease, ocular-surface disorders, and glaucoma treatment. In addition, members of the faculty direct a major national multicenter clinical trial -- the Advanced Glaucoma Intervention Study -- and participate in ongoing (eg, CRYO-ROP, GLT) and planned (eg, optic neuropathy, ocular trauma) multi-center studies. The Worthen Center provides dedicated and integrated space in which new, important clinical vision research studies are vigorously pursued. This award provides crucial staff resources for the development of such projects: a PhD-level epidemiologist-biostatistician to serve as co-PI on clinical research projects and a clinical projects coordinator who is expert in the administrative aspects of conducting vision research with patients.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21EY007744-04
Application #
3443806
Study Section
Vision Research and Training Committee (VSN)
Project Start
1988-04-01
Project End
1993-03-31
Budget Start
1991-04-01
Budget End
1992-03-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Georgetown University
Department
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Javitt, J C; Aiello, L P (1996) Cost-effectiveness of detecting and treating diabetic retinopathy. Ann Intern Med 124:164-9
Patel, K H; Javitt, J C; Tielsch, J M et al. (1995) Incidence of acute angle-closure glaucoma after pharmacologic mydriasis. Am J Ophthalmol 120:709-17
Javitt, J C; Aiello, L P; Chiang, Y et al. (1994) Preventive eye care in people with diabetes is cost-saving to the federal government. Implications for health-care reform. Diabetes Care 17:909-17
Javitt, J C; Brenner, M H; Curbow, B et al. (1993) Outcomes of cataract surgery. Improvement in visual acuity and subjective visual function after surgery in the first, second, and both eyes. Arch Ophthalmol 111:686-91
Canner, J K; Javitt, J C; McBean, A M (1992) National outcomes of cataract extraction. III. Corneal edema and transplant following inpatient surgery. Arch Ophthalmol 110:1137-42
DeiCas, R; Street, D A; Javitt, J C (1992) Assessment of visual acuity via a telephone interview. Arch Ophthalmol 110:1279-82
Street, D A; Javitt, J C (1992) National five-year mortality after inpatient cataract extraction. Am J Ophthalmol 113:263-8
Chiang, Y P; Bassi, L J; Javitt, J C (1992) Federal budgetary costs of blindness. Milbank Q 70:319-40
Javitt, J C; McBean, A M; Nicholson, G A et al. (1991) Undertreatment of glaucoma among black Americans. N Engl J Med 325:1418-22