Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Unknown (R23)
Project #
5R23HL036390-02
Application #
3449253
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1986-04-01
Project End
1987-06-30
Budget Start
1987-04-01
Budget End
1987-06-30
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Oparil, S; Wyss, J M; Yang, R H et al. (1990) Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanism. Am J Hypertens 3:179S-188S
Yang, R H; Igarashi, Y; Wyss, J M et al. (1990) Dopamine D2 receptors in the posterior region of the nucleus tractus solitarius mediate the central pressor action of quinpirole (LY171555). Brain Res Bull 24:97-103
Sripairojthikoon, W; Wyss, J M (1989) High NaCl diets increase alpha 2-adrenoceptors in renal cortex and medulla of NaCl-sensitive spontaneously hypertensive rats. Eur J Pharmacol 167:355-65
Yang, R H; Jin, H K; Chen, Y F et al. (1989) Dietary Ca2+ supplementation prevents the exaggerated responsiveness of anterior hypothalamic alpha 2-adrenoceptors in NaCl-loaded spontaneously hypertensive rats. J Cardiovasc Pharmacol 13:162-7
Sripairojthikoon, W; Oparil, S; Wyss, J M (1989) Renal nerve contribution to NaCl-exacerbated hypertension in spontaneously hypertensive rats. Hypertension 14:184-90
Wyss, J M; Yang, R H; Jin, H K et al. (1988) Hypothalamic microinjection of alpha 2-adrenoceptor agonists causes greater sympathoinhibition in spontaneously hypertensive rats on high NaCl diets. J Hypertens 6:805-13
Chen, Y F; Yang, R H; Jin, H et al. (1988) Exaggerated depressor response to 6-iodoamiloride in NaCl-sensitive spontaneously hypertensive rats. Am J Med Sci 296:78-83
Chen, Y F; Meng, Q C; Wyss, J M et al. (1988) High NaCl diet reduces hypothalamic norepinephrine turnover in hypertensive rats. Hypertension 11:55-62
Oparil, S; Meng, Q C; Chen, Y F et al. (1988) Genetic basis of NaCl-sensitive hypertension. J Cardiovasc Pharmacol 12 Suppl 3:S56-69
Chen, Y F; Jin, H K; Gist, R et al. (1987) Blunted responsiveness of posterior hypothalamic norepinephrine to quinpirole in DOCA/NaCl hypertensive rats. Brain Res Bull 18:563-8

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