This research transition proposal will train and provide infrastructure support, mentoring, and guided research experiences for fellows and faculty in clinical mental health services research (CMHSR) to enable them to translate clinical research findings into clinical practice for the care of patients with severe and persistent mental illnesses (SPMI). Of specific interest are assessment, treatment, and rehabilitative methods, for children, adolescents, and adults, the efficacy of which have been demonstrated in research settings. This research will adapt, test, and refine these methods to improve the quality and outcome of care for individuals with SPMIs in the public sector. At present, though known for its clinical research expertise in schizophrenia, mood disorders, and Alzheimer's Disease, U.T. Southwestern Medical Center faculty do not possess extensive expertise in CMHSR. This research transition proposal provides for the development of such expertise through: 1) courses and didactic workshops; 2) mentoring by experienced clinical mental health services researchers outside the institution with consultation from clinical researchers at U.T. Southwestern; and 3) supervised execution of pilot projects that pass careful scientific scrutiny by services research experts. These pilot projects, if promising, will lead to independent, peer-reviewed applications to address specific services research questions. This proposal builds upon the momentum initiated by the Mental Health Connections research program, a new state funded collaborative research program between U.T. Southwestern and the Dallas County Mental Health/Mental Retardation Center (DCMHMR) which test clinical innovations and service system modifications to improve assessment, treatment and service delivery in DCMHMR. This research transition proposal will provide the essential administrative, educational, and scientific infrastructure needed to develop scientific excellence in the area of CMHSR. Furthermore, the investigators' initial efforts with adults will be expanded to include research on children and adolescents and those in the justice system. The net result of this 5 years of support will be a well-trained cadre of collaborating, multidisciplinary, CMHSR researchers able to conduct """"""""state-of-the-art"""""""" research focused on public sector psychiatric care for people with SPMIs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Resource-Related Research Projects (R24)
Project #
5R24MH053799-05
Application #
2675311
Study Section
Special Emphasis Panel (SRCM (15))
Project Start
1994-09-30
Project End
2000-08-31
Budget Start
1998-09-01
Budget End
2000-08-31
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Garlow, Steven J (2014) Response to the letter from Marc B Stone, MD; Tarek A Hammad, MD, PhD, MSc, MS. J Psychiatr Res 48:133-4
Warden, D; Trivedi, M H; Carmody, T J et al. (2010) Anticipated Benefits of Care (ABC): psychometrics and predictive value in psychiatric disorders. Psychol Med 40:955-65
Warden, Diane; Rush, A John; Carmody, Thomas J et al. (2009) Predictors of attrition during one year of depression treatment: a roadmap to personalized intervention. J Psychiatr Pract 15:113-24
Bernstein, Ira H; Rush, A John; Suppes, Trisha et al. (2009) A psychometric evaluation of the clinician-rated Quick Inventory of Depressive Symptomatology (QIDS-C16) in patients with bipolar disorder. Int J Methods Psychiatr Res 18:138-46
Bernstein, Ira H; Rush, A John; Carmody, Thomas J et al. (2007) Clinical vs. self-report versions of the quick inventory of depressive symptomatology in a public sector sample. J Psychiatr Res 41:239-46
Toprac, Marcia G; Dennehy, Ellen B; Carmody, Thomas J et al. (2006) Implementation of the Texas Medication Algorithm Project patient and family education program. J Clin Psychiatry 67:1362-72
Kashner, T Michael; Rush, A John; Crismon, M Lynn et al. (2006) An empirical analysis of cost outcomes of the Texas Medication Algorithm Project. Psychiatr Serv 57:648-59
Adli, Mazda; Bauer, Michael; Rush, A John (2006) Algorithms and collaborative-care systems for depression: are they effective and why? A systematic review. Biol Psychiatry 59:1029-38
Rush, A John; Carmody, Thomas J; Ibrahim, Hisham M et al. (2006) Comparison of self-report and clinician ratings on two inventories of depressive symptomatology. Psychiatr Serv 57:829-37
Dennehy, Ellen B; Suppes, Trisha; Rush, A John et al. (2005) Does provider adherence to a treatment guideline change clinical outcomes for patients with bipolar disorder? Results from the Texas Medication Algorithm Project. Psychol Med 35:1695-706

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