The Stanford Molecular Imaging Scholars (SMIS) program is an integrated, cross-disciplinary postdoctoral training program at Stanford University that brings together 45 faculty mentors from 15 departments in the Schools of Medicine, Engineering, and Humanities and Sciences. Molecular imaging, the non-invasive monitoring of specific molecular and biochemical processes in living organisms, continues to expand its applications in the detection and management of cancer. We train, on average, ~7 postdoctoral trainees per year. SMIS faculty mentors provide a diverse training environment spanning biology, physics, mathematics/biocomputation/ biomedical informatics, engineering, chemistry, biochemistry, cancer biology, immunology, and medical sciences. The centerpiece of the SMIS program is the opportunity for trainees (PhD or MD with an emphasis on PhD) to conduct innovative molecular imaging research that is co-mentored by faculty in complementary disciplines. SMIS trainees also engage in specialized coursework, seminars, national conferences, clinical rounds, including ethics training and the responsible conduct of research. The three-year program culminates with the preparation and review of a mock grant, in support of trainee transition to an independent career in cancer molecular imaging. During this initial 3.7 year period, 14 trainees have entered the SMIS program;8 are currently enrolled and 6 have completed the program as of this writing. Two additional trainees will complete in August, 2010, bringing the total number of """"""""SMIS graduates"""""""" to 8. Those who have moved on are either in faculty positions, other academic positions, or working in biotechnology. Demand for the SMIS training is high;we now receive, on average, more than 20 applications per year from qualified candidates seeking placement in our program, which can accommodate only 2-4 new trainees per year. For the upcoming cycle, we propose an enriched SMIS program that achieves the following: expands our recently added Program Area in Nanotechnology;strategically selects additional faculty mentors;presents improvement in all other training and career development components;expands leadership for our mock grant program and our clinical exposure component;and pursues rigorous recruitment of underrepresented minority candidates. The goal of the SMIS program is to continue to provide talented young investigators with the scientific and professional education/career development opportunities to become leaders in the field of molecular imaging of cancer.

Public Health Relevance

The Stanford Molecular Imaging Scholars (SMIS) program is an integrated, cross-disciplinary postdoctoral training program that prepares young investigators for research careers in the field of molecular imaging of cancer. Molecular imaging is a science that allows visualization of specific molecules and biochemical processes in intact living organisms, and provides powerful tools for the study of disease. SMIS trainees develop innovative molecular imaging approaches for the diagnosis and management of cancer, including treatment selection and evaluation of therapy response.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Education Projects (R25)
Project #
5R25CA118681-09
Application #
8728570
Study Section
Subcommittee B - Comprehensiveness (NCI)
Program Officer
Perkins, Susan N
Project Start
2005-12-01
Project End
2016-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
9
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
City
Stanford
State
CA
Country
United States
Zip Code
94304
Abbaszadeh, Shiva; Chinn, Garry; Levin, Craig S (2018) Positioning true coincidences that undergo inter-and intra-crystal scatter for a sub-mm resolution cadmium zinc telluride-based PET system. Phys Med Biol 63:025012
Cates, Joshua W; Levin, Craig S (2018) Evaluation of a clinical TOF-PET detector design that achieves ?100 ps coincidence time resolution. Phys Med Biol 63:115011
Wilson, Katheryne E; Bachawal, Sunitha V; Abou-Elkacem, Lotfi et al. (2017) Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent. Theranostics 7:1463-1476
Cates, Joshua W; Bieniosek, Matthew F; Levin, Craig S (2017) Highly multiplexed signal readout for a time-of-flight positron emission tomography detector based on silicon photomultipliers. J Med Imaging (Bellingham) 4:011012
Hori, Sharon Seiko; Lutz, Amelie M; Paulmurugan, Ramasamy et al. (2017) A Model-Based Personalized Cancer Screening Strategy for Detecting Early-Stage Tumors Using Blood-Borne Biomarkers. Cancer Res 77:2570-2584
Chang, Chen-Ming; Cates, Joshua W; Levin, Craig S (2017) Time-over-threshold for pulse shape discrimination in a time-of-flight phoswich PET detector. Phys Med Biol 62:258-271
Abbaszadeh, Shiva; Levin, Craig S (2017) New-generation small animal positron emission tomography system for molecular imaging. J Med Imaging (Bellingham) 4:011008
Bieniosek, M F; Cates, J W; Levin, C S (2016) A multiplexed TOF and DOI capable PET detector using a binary position sensitive network. Phys Med Biol 61:7639-7651
Van de Sompel, Dominique; Sasportas, Laura S; Jokerst, Jesse V et al. (2016) Comparison of Deconvolution Filters for Photoacoustic Tomography. PLoS One 11:e0152597
Valluru, Keerthi S; Wilson, Katheryne E; Willmann, Jürgen K (2016) Photoacoustic Imaging in Oncology: Translational Preclinical and Early Clinical Experience. Radiology 280:332-49

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