In response to PA 99-093, the UCLA Integrated Substance Abuse Programs submits this application for funding of the Clinical Research Education for Drug Abuse Professionals training program. The program will develop professionals in health disciplines involving clinical research pertaining to the study of drug abuse and its treatment, starting in the first year with two M.D. or Ph.D.-level trainees and expanding in future project years to three per year. This comprehensive education program will consist of a two-year period of coordinated clinical research training combining coursework, seminars, and practical experience. Trainees will acquire (1) a comprehensive education in a variety of disciplines, ranging from epidemiology of drug abuse to neurobiology of addiction and consequent effects on the brain; and (2) in-depth clinical research experience, with a focus on conduct of clinical trials research in both institutional and community-based settings. After the first three-quarters of the first year of the program, in which trainees gain knowledge in a core curriculum, trainees will spend the remainder of their time in """"""""hands-on"""""""" clinical research at inpatient and outpatient sites. Given the applicant organization?s vast research portfolio, its history of research training, its distinguished academic affiliation, and its interrelated capacities in drug abuse research, clinical practice, and clinical training for specific projects, the proposed program will fill a pressing need for dedicated formal training of clinical researchers, setting the foundation for a high-quality program that will continue to produce the drug abuse professionals required to investigate and address drug abuse and its consequences.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Education Projects (R25)
Project #
5R25DA014593-05
Application #
7093578
Study Section
Special Emphasis Panel (ZDA1-MXG-S (16))
Program Officer
Czechowicz, Dorynne D
Project Start
2002-09-30
Project End
2008-05-31
Budget Start
2006-06-01
Budget End
2008-05-31
Support Year
5
Fiscal Year
2006
Total Cost
$309,597
Indirect Cost
Name
University of California Los Angeles
Department
Psychiatry
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Mahoney 3rd, James J; De La Garza 2nd, Richard; Jackson, Brian J et al. (2014) The relationship between sleep and drug use characteristics in participants with cocaine or methamphetamine use disorders. Psychiatry Res 219:367-71
Chang, L C; Mahoney 3rd, J J; Raty, S R et al. (2013) Neurocognitive effects following an overnight call shift on faculty anesthesiologists. Acta Anaesthesiol Scand 57:1051-7
Mahoney, James J; Jackson, Brian J; Kalechstein, Ari D et al. (2012) Acute modafinil exposure reduces daytime sleepiness in abstinent methamphetamine-dependent volunteers. Int J Neuropsychopharmacol 15:1241-9
Mahoney 3rd, James J; Jackson, Brian J; Kalechstein, Ari D et al. (2011) Acute, low-dose methamphetamine administration improves attention/information processing speed and working memory in methamphetamine-dependent individuals displaying poorer cognitive performance at baseline. Prog Neuropsychopharmacol Biol Psychiatry 35:459-65
Mahoney 3rd, James J; Hawkins, Rollin Y; De La Garza 2nd, Richard et al. (2010) Relationship between gender and psychotic symptoms in cocaine-dependent and methamphetamine-dependent participants. Gend Med 7:414-21
De La Garza 2nd, Richard; Ashbrook, Liza H; Evans, Sarah E et al. (2009) Influence of verbal recall of a recent stress experience on anxiety and desire for cocaine in non-treatment seeking, cocaine-addicted volunteers. Am J Addict 18:481-7
Lin, Shen-Nan; Lamm, Lolita; Newton, Thomas F et al. (2009) A liquid chromatography-electrospray ionization-tandem mass spectrometry method for quantitation of aripiprazole in human plasma. J Anal Toxicol 33:237-42
Culbertson, C; De La Garza 2nd, R; Costello, M et al. (2009) Unrestricted access to methamphetamine or cocaine in the past is associated with increased current use. Int J Neuropsychopharmacol 12:677-85
De La Garza, Richard; Shoptaw, Steve; Newton, Thomas F (2008) Evaluation of the cardiovascular and subjective effects of rivastigmine in combination with methamphetamine in methamphetamine-dependent human volunteers. Int J Neuropsychopharmacol 11:729-41
De La Garza 2nd, R; Mahoney 3rd, J J; Culbertson, C et al. (2008) The acetylcholinesterase inhibitor rivastigmine does not alter total choices for methamphetamine, but may reduce positive subjective effects, in a laboratory model of intravenous self-administration in human volunteers. Pharmacol Biochem Behav 89:200-8

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