Ethanol and Excitatory Amino Acid Function in Brain

Rooney, Thomas A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29AA010413-02
• Application #: 2047052
• Study Section: Biochemistry, Physiology and Medicine Subcommittee (ALCB)
• Project Start: 1995-07-01
• Project End: 2000-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: Thomas Jefferson University
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 061197161
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19107

Publications

Zhang, F X; Rubin, R; Rooney, T A (1998) N-Methyl-D-aspartate inhibits apoptosis through activation of phosphatidylinositol 3-kinase in cerebellar granule neurons. A role for insulin receptor substrate-1 in the neurotrophic action of n-methyl-D-aspartate and its inhibition by ethanol. J Biol Chem 273:26596-602

Zhang, F X; Rubin, R; Rooney, T A (1998) Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling. J Neurochem 71:196-204

Rooney, T A; Joseph, S K; Queen, C et al. (1996) Cyclic GMP induces oscillatory calcium signals in rat hepatocytes. J Biol Chem 271:19817-25