Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AG006854-05
Application #
3453062
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1992-08-01
Budget End
1993-07-31
Support Year
5
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Demaria, S; Schwab, R; Bushkin, Y (1992) The origin and fate of beta 2m-free MHC class I molecules induced on activated T cells. Cell Immunol 142:103-13
Schwab, R; Russo, C; Weksler, M E (1992) Altered major histocompatibility complex-restricted antigen recognition by T cells from elderly humans. Eur J Immunol 22:2989-93
Weksler, M E; Schwab, R (1992) The immunogenetics of immune senescence. Exp Clin Immunogenet 9:182-7
Bovbjerg, D H; Kim, Y T; Schwab, R et al. (1991) ""Cross-wiring"" of the immune response in old mice: increased autoantibody response despite reduced antibody response to nominal antigen. Cell Immunol 135:519-25
Gamble, D A; Schwab, R; Weksler, M E et al. (1990) Decreased steady state c-myc mRNA in activated T cell cultures from old humans is caused by a smaller proportion of T cells that transcribe the c-myc gene. J Immunol 144:3569-73
Schwab, R; Pfeffer, L M; Szabo, P et al. (1990) Defective expression of high affinity IL-2 receptors on activated T cells from aged humans. Int Immunol 2:239-46
Weksler, M E; Schwab, R; Huetz, F et al. (1989) Cellular basis of autoantibody production in old mice. Trans Assoc Am Physicians 102:55-8