Conformational Peptides to Probes Immune Responses

Kaumaya, Pravin T.P

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 7R29AI025790-03
• Application #: 3454561
• Study Section: Immunobiology Study Section (IMB)
• Project Start: 1989-09-01
• Project End: 1993-08-31
• Budget Start: 1989-09-01
• Budget End: 1990-08-31
• Support Year: 3
• Fiscal Year: 1989

Institution

• Name: Ohio State University
• Type: Schools of Medicine
• DUNS #: 098987217
• City: Columbus
• State: OH
• Country: United States
• Zip Code: 43210

Publications

Srinivasan, M; Domanico, S Z; Kaumaya, P T et al. (1993) Peptides of 23 residues or greater are required to stimulate a high affinity class II-restricted T cell response. Eur J Immunol 23:1011-6

Kobs-Conrad, S; Lee, H; DiGeorge, A M et al. (1993) Engineered topographic determinants with alpha beta, beta alpha beta, and beta alpha beta alpha topologies show high affinity binding to native protein antigen (lactate dehydrogenase-C4). J Biol Chem 268:25285-95

Kaumaya, P T; VanBuskirk, A M; Goldberg, E et al. (1992) Design and immunological properties of topographic immunogenic determinants of a protein antigen (LDH-C4) as vaccines. J Biol Chem 267:6338-46

Kaumaya, P T; Berndt, K D; Heidorn, D B et al. (1990) Synthesis and biophysical characterization of engineered topographic immunogenic determinants with alpha alpha topology. Biochemistry 29:13-23