Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI026150-03
Application #
3454621
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1988-12-01
Project End
1993-11-30
Budget Start
1990-12-01
Budget End
1991-11-30
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Henry M. Jackson Fdn for the Adv Mil/Med
Department
Type
DUNS #
City
Rockville
State
MD
Country
United States
Zip Code
20817
Urban Jr, J F; Maliszewski, C R; Madden, K B et al. (1995) IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice. J Immunol 154:4675-84
Katona, I M; Urban Jr, J F; Finkelman, F D et al. (1995) Cytokine regulation of intestinal mastocytosis in Nippostrongylus brasiliensis infection. Adv Exp Med Biol 371B:971-3
Thyphronitis, G; Katona, I M; Gause, W C et al. (1993) Germline and productive C epsilon gene expression during in vivo IgE responses. J Immunol 151:4128-36
Urban Jr, J F; Madden, K B; Cheever, A W et al. (1993) IFN inhibits inflammatory responses and protective immunity in mice infected with the nematode parasite, Nippostrongylus brasiliensis. J Immunol 151:7086-94
Urban Jr, J F; Madden, K B; Svetic, A et al. (1992) The importance of Th2 cytokines in protective immunity to nematodes. Immunol Rev 127:205-20
Finkelman, F D; Svetic, A; Gresser, I et al. (1991) Regulation by interferon alpha of immunoglobulin isotype selection and lymphokine production in mice. J Exp Med 174:1179-88
Urban Jr, J F; Katona, I M; Paul, W E et al. (1991) Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice. Proc Natl Acad Sci U S A 88:5513-7
Madden, K B; Urban Jr, J F; Ziltener, H J et al. (1991) Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis. J Immunol 147:1387-91
Katona, I M; Urban Jr, J F; Kang, S S et al. (1991) IL-4 requirements for the generation of secondary in vivo IgE responses. J Immunol 146:4215-21
Finkelman, F D; Urban Jr, J F; Beckmann, M P et al. (1991) Regulation of murine in vivo IgG and IgE responses by a monoclonal anti-IL-4 receptor antibody. Int Immunol 3:599-607

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