Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI027863-04
Application #
3455105
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1990-01-01
Project End
1993-07-31
Budget Start
1993-01-01
Budget End
1993-07-31
Support Year
4
Fiscal Year
1993
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
van Rensburg, Julia J; Lin, Huaiying; Gao, Xiang et al. (2015) The Human Skin Microbiome Associates with the Outcome of and Is Influenced by Bacterial Infection. MBio 6:e01315-15
Gangaiah, Dharanesh; Webb, Kristen M; Humphreys, Tricia L et al. (2015) Haemophilus ducreyi Cutaneous Ulcer Strains Are Nearly Identical to Class I Genital Ulcer Strains. PLoS Negl Trop Dis 9:e0003918
Holley, Concerta L; Zhang, Xinjun; Fortney, Kate R et al. (2015) DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans. Infect Immun 83:3281-92
Holley, Concerta; Gangaiah, Dharanesh; Li, Wei et al. (2014) A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes. Infect Immun 82:3492-502
Gangaiah, Dharanesh; Zhang, Xinjun; Baker, Beth et al. (2014) Haemophilus ducreyi RpoE and CpxRA appear to play distinct yet complementary roles in regulation of envelope-related functions. J Bacteriol 196:4012-25
Zhang, Xinjun; Gangaiah, Dharanesh; Munson Jr, Robert S et al. (2014) Correcting imbalanced reads coverage in bacterial transcriptome sequencing with extreme deep coverage. Int J Comput Biol Drug Des 7:195-213
Gangaiah, Dharanesh; Li, Wei; Fortney, Kate R et al. (2013) Carbon storage regulator A contributes to the virulence of Haemophilus ducreyi in humans by multiple mechanisms. Infect Immun 81:608-17
Gangaiah, Dharanesh; Zhang, Xinjun; Fortney, Kate R et al. (2013) Activation of CpxRA in Haemophilus ducreyi primarily inhibits the expression of its targets, including major virulence determinants. J Bacteriol 195:3486-502
Labandeira-Rey, Maria; Dodd, Dana A; Brautigam, Chad A et al. (2013) The Haemophilus ducreyi Fis protein is involved in controlling expression of the lspB-lspA2 operon and other virulence factors. Infect Immun 81:4160-70
Labandeira-Rey, Maria; Dodd, Dana; Fortney, Kate R et al. (2011) A Haemophilus ducreyi CpxR deletion mutant is virulent in human volunteers. J Infect Dis 203:1859-65

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