Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
7R29AI028508-04
Application #
3455267
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1989-09-30
Project End
1994-08-31
Budget Start
1992-03-01
Budget End
1992-08-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Fukazawa, T; Reedquist, K A; Trub, T et al. (1995) The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J Biol Chem 270:19141-50
Fukazawa, T; Reedquist, K A; Panchamoorthy, G et al. (1995) T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38. J Biol Chem 270:20177-82
Bukowski, J F; Morita, C T; Tanaka, Y et al. (1995) V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer. J Immunol 154:998-1006
Morita, C T; Beckman, E M; Bukowski, J F et al. (1995) Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity 3:495-507
Panchamoorthy, G; Fukazawa, T; Stolz, L et al. (1994) Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn. Mol Cell Biol 14:6372-85
Ohmen, J D; Moy, R L; Zovich, D et al. (1994) Selective accumulation of T cells according to T-cell receptor V beta gene usage in skin cancer. J Invest Dermatol 103:751-7
Delmolino, L; Band, H; Band, V (1993) Expression and stability of p53 protein in normal human mammary epithelial cells. Carcinogenesis 14:827-32
Yamamura, M; Modlin, R L; Ohmen, J D et al. (1993) Local expression of antiinflammatory cytokines in cancer. J Clin Invest 91:1005-10
Barnes, P F; Grisso, C L; Abrams, J S et al. (1992) Gamma delta T lymphocytes in human tuberculosis. J Infect Dis 165:506-12
Uyemura, K; Deans, R J; Band, H et al. (1991) Evidence for clonal selection of gamma/delta T cells in response to a human pathogen. J Exp Med 174:683-92

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