Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI030126-05
Application #
2065456
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1991-08-01
Project End
1997-05-31
Budget Start
1995-06-01
Budget End
1997-05-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Gay, L S; Wilson, M E; Donelson, J E (1996) The promoter for the ribosomal RNA genes of Leishmania chagasi. Mol Biochem Parasitol 77:193-200
Streit, J A; Donelson, J E; Agey, M W et al. (1996) Developmental changes in the expression of Leishmania chagasi gp63 and heat shock protein in a human macrophage cell line. Infect Immun 64:1810-8
Wilson, M E; Streit, J A (1996) Visceral leishmaniasis. Gastroenterol Clin North Am 25:535-51
Wilson, M E; Sandor, M; Blum, A M et al. (1996) Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J Immunol 156:2231-9
Li, S; Wilson, M E; Donelson, J E (1996) Leishmania chagasi: a gene encoding a protein kinase with a catalytic domain structurally related to MAP kinase kinase. Exp Parasitol 82:87-96
Andersen, K A; Britigan, B E; Wilson, M E (1996) Short report: regulation of inducible heat shock protein 70 genes in Leishmania chagasi. Am J Trop Med Hyg 54:471-4
Roberts, S C; Wilson, M E; Donelson, J E (1995) Developmentally regulated expression of a novel 59-kDa product of the major surface protease (Msp or gp63) gene family of Leishmania chagasi. J Biol Chem 270:8884-92
Wilson, M E; Young, B M; Andersen, K P et al. (1995) A recombinant Leishmania chagasi antigen that stimulates cellular immune responses in infected mice. Infect Immun 63:2062-9
Ramamoorthy, R; Swihart, K G; McCoy, J J et al. (1995) Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes. J Biol Chem 270:12133-9
Cain, C; Stone, M S; Thieberg, M et al. (1994) Nonhealing genital ulcers. Cutaneous leishmaniasis. Arch Dermatol 130:1313, 1315-6

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