Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI033143-03
Application #
2068139
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1994-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Busch, D H; Kerksiek, K M; Pamer, E G (2000) Differing roles of inflammation and antigen in T cell proliferation and memory generation. J Immunol 164:4063-70
Busch, D H; Pamer, E G (1999) T cell affinity maturation by selective expansion during infection. J Exp Med 189:701-10
Busch, D H; Kerksiek, K; Pamer, E G (1999) Processing of Listeria monocytogenes antigens and the in vivo T-cell response to bacterial infection. Immunol Rev 172:163-9
Vijh, S; Pilip, I M; Pamer, E G (1999) Noncompetitive expansion of cytotoxic T lymphocytes specific for different antigens during bacterial infection. Infect Immun 67:1303-9
Busch, D H; Pamer, E G (1999) T lymphocyte dynamics during Listeria monocytogenes infection. Immunol Lett 65:93-8
Busch, D H; Pilip, I M; Vijh, S et al. (1998) Coordinate regulation of complex T cell populations responding to bacterial infection. Immunity 8:353-62
Busch, D H; Pilip, I; Pamer, E G (1998) Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection. J Exp Med 188:61-70
Busch, D H; Pamer, E G (1998) MHC class I/peptide stability: implications for immunodominance, in vitro proliferation, and diversity of responding CTL. J Immunol 160:4441-8
Vijh, S; Pilip, I M; Pamer, E G (1998) Effect of antigen-processing efficiency on in vivo T cell response magnitudes. J Immunol 160:3971-7
Busch, D H; Bouwer, H G; Hinrichs, D et al. (1997) A nonamer peptide derived from Listeria monocytogenes metalloprotease is presented to cytolytic T lymphocytes. Infect Immun 65:5326-9

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