Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI033588-04
Application #
2068645
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1993-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Surgery
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Bingaman, A W; Ha, J; Durham, M M et al. (2001) Analysis of the CD40 and CD28 pathways on alloimmune responses by CD4+ T cells in vivo. Transplantation 72:1286-92
Ha, J; Bingaman, A W; Durham, M M et al. (2001) Aggressive skin allograft rejection in CD28-/- mice independent of the CD40/CD40L costimulatory pathway. Transpl Immunol 9:13-7
Bingaman, A W; Pearson, T C; Larsen, C P (2000) The role of CD40L in T cell-dependent nitric oxide production by murine macrophages. Transpl Immunol 8:195-202
Bingaman, A W; Waitze, S Y; Alexander, D Z et al. (2000) Transplantation of the bone marrow microenvironment leads to hematopoietic chimerism without cytoreductive conditioning. Transplantation 69:2491-6
Niimi, M; Pearson, T C; Larsen, C P et al. (1998) The role of the CD40 pathway in alloantigen-induced hyporesponsiveness in vivo. J Immunol 161:5331-7
Elwood, E T; Larsen, C P; Cho, H R et al. (1998) Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade. Transplantation 65:1422-8
Konieczny, B T; Dai, Z; Elwood, E T et al. (1998) IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways. J Immunol 160:2059-64
Pearson, T C; Alexander, D Z; Corbascio, M et al. (1997) Analysis of the B7 costimulatory pathway in allograft rejection. Transplantation 63:1463-9
Weber, C J; Hagler, M K; Chryssochoos, J T et al. (1996) CTLA4-Ig prolongs survival of microencapsulated rabbit islet xenografts in spontaneously diabetic Nod mice. Transplant Proc 28:821-3
Pearson, T C; Alexander, D Z; Hendrix, R et al. (1996) CTLA4-Ig plus bone marrow induces long-term allograft survival and donor specific unresponsiveness in the murine model. Evidence for hematopoietic chimerism. Transplantation 61:997-1004

Showing the most recent 10 out of 15 publications