Structure-Function Analysis of Shiga-Like Toxin

Hovde, Carolyn J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29AI033981-04
• Application #: 2069037
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1993-09-01
• Project End: 1998-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Idaho
• Department: Microbiology/Immun/Virology
• Type: Schools of Earth Sciences/Natur
• City: Moscow
• State: ID
• Country: United States
• Zip Code: 83844

Publications

Grauke, Luke J; Kudva, Indira T; Yoon, Jang Won et al. (2002) Gastrointestinal tract location of Escherichia coli O157:H7 in ruminants. Appl Environ Microbiol 68:2269-77

Magnuson, B A; Davis, M; Hubele, S et al. (2000) Ruminant gastrointestinal cell proliferation and clearance of Escherichia coli O157:H7. Infect Immun 68:3808-14

Ferens, W A; Hovde, C J (2000) Antiviral activity of shiga toxin 1: suppression of bovine leukemia virus-related spontaneous lymphocyte proliferation. Infect Immun 68:4462-9

Hovde, C J; Austin, P R; Cloud, K A et al. (1999) Effect of cattle diet on Escherichia coli O157:H7 acid resistance. Appl Environ Microbiol 65:3233-5

Kudva, I T; Jelacic, S; Tarr, P I et al. (1999) Biocontrol of Escherichia coli O157 with O157-specific bacteriophages. Appl Environ Microbiol 65:3767-73

Suhan, M L; Hovde, C J (1998) Disruption of an internal membrane-spanning region in Shiga toxin 1 reduces cytotoxicity. Infect Immun 66:5252-9

Suh, J K; Hovde, C J; Robertus, J D (1998) Shiga toxin attacks bacterial ribosomes as effectively as eucaryotic ribosomes. Biochemistry 37:9394-8

Kudva, I T; Blanch, K; Hovde, C J (1998) Analysis of Escherichia coli O157:H7 survival in ovine or bovine manure and manure slurry. Appl Environ Microbiol 64:3166-74

Kudva, I T; Hunt, C W; Williams, C J et al. (1997) Evaluation of dietary influences on Escherichia coli O157:H7 shedding by sheep. Appl Environ Microbiol 63:3878-86

Kudva, I T; Hatfield, P G; Hovde, C J (1997) Characterization of Escherichia coli O157:H7 and other Shiga toxin-producing E. coli serotypes isolated from sheep. J Clin Microbiol 35:892-9