Structure and Function of Paramyxovirus L Protein

Parks, Griffith D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29AI034329-04
• Application #: 2069444
• Study Section: Experimental Virology Study Section (EVR)
• Project Start: 1993-08-01
• Project End: 1998-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: Wake Forest University Health Sciences
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 041418799
• City: Winston-Salem
• State: NC
• Country: United States
• Zip Code: 27106

Publications

Murphy, S K; Ito, Y; Parks, G D (1998) A functional antigenomic promoter for the paramyxovirus simian virus 5 requires proper spacing between an essential internal segment and the 3' terminus. J Virol 72:10-9

Rassa, J C; Parks, G D (1998) Molecular basis for naturally occurring elevated readthrough transcription across the M-F junction of the paramyxovirus SV5. Virology 247:274-86

Murphy, S K; Parks, G D (1997) Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5. Virology 232:145-57

Parks, G D (1996) Differential effects of changes in the length of a signal/anchor domain on membrane insertion, subunit assembly, and intracellular transport of a type II integral membrane protein. J Biol Chem 271:7187-95

Parks, G D; Pohlmann, S (1995) Structural requirements in the membrane-spanning domain of the paramyxovirus HN protein for the formation of a stable tetramer. Virology 213:263-70

Parks, G D (1994) Mapping of a region of the paramyxovirus L protein required for the formation of a stable complex with the viral phosphoprotein P. J Virol 68:4862-72