Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI036373-03
Application #
2072625
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1994-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Santa Barbara
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Santa Barbara
State
CA
Country
United States
Zip Code
93106
Julio, S M; Heithoff, D M; Mahan, M J (2000) ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis. J Bacteriol 182:1558-63
Heithoff, D M; Sinsheimer, R L; Low, D A et al. (2000) In vivo gene expression and the adaptive response: from pathogenesis to vaccines and antimicrobials. Philos Trans R Soc Lond B Biol Sci 355:633-42
Handfield, M; Lehoux, D E; Sanschagrin, F et al. (2000) In vivo-induced genes in Pseudomonas aeruginosa. Infect Immun 68:2359-62
Heithoff, D M; Sinsheimer, R L; Low, D A et al. (1999) An essential role for DNA adenine methylation in bacterial virulence. Science 284:967-70
Heithoff, D M; Conner, C P; Hentschel, U et al. (1999) Coordinate intracellular expression of Salmonella genes induced during infection. J Bacteriol 181:799-807
Conner, C P; Heithoff, D M; Julio, S M et al. (1998) Differential patterns of acquired virulence genes distinguish Salmonella strains. Proc Natl Acad Sci U S A 95:4641-5
Julio, S M; Conner, C P; Heithoff, D M et al. (1998) Directed formation of chromosomal deletions in Salmonella typhimurium: targeting of specific genes induced during infection. Mol Gen Genet 258:178-81
Conner, C P; Heithoff, D M; Mahan, M J (1998) In vivo gene expression: contributions to infection, virulence, and pathogenesis. Curr Top Microbiol Immunol 225:1-12
Handfield, M; Schweizer, H P; Mahan, M J et al. (1998) ASD-GFP vectors for in vivo expression technology in Pseudomonas aeruginosa and other gram-negative bacteria. Biotechniques 24:261-4
Rainey, P B; Heithoff, D M; Mahan, M J (1997) Single-step conjugative cloning of bacterial gene fusions involved in microbe-host interactions. Mol Gen Genet 256:84-7

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