Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI038190-02
Application #
2075146
Study Section
AIDS and Related Research Study Section 5 (ARRE)
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Traynor, T R; Huffnagle, G B (2001) Role of chemokines in fungal infections. Med Mycol 39:41-50
Traynor, T R; Kuziel, W A; Toews, G B et al. (2000) CCR2 expression determines T1 versus T2 polarization during pulmonary Cryptococcus neoformans infection. J Immunol 164:2021-7
Huffnagle, G B; Traynor, T R; McDonald, R A et al. (2000) Leukocyte recruitment during pulmonary Cryptococcus neoformans infection. Immunopharmacology 48:231-6
Huffnagle, G B; McNeil, L K (1999) Dissemination of C. neoformans to the central nervous system: role of chemokines, Th1 immunity and leukocyte recruitment. J Neurovirol 5:76-81
Huffnagle, G B; McNeil, L K; McDonald, R A et al. (1999) Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans. J Immunol 163:4642-6
Huffnagle, G B; Boyd, M B; Street, N E et al. (1998) IL-5 is required for eosinophil recruitment, crystal deposition, and mononuclear cell recruitment during a pulmonary Cryptococcus neoformans infection in genetically susceptible mice (C57BL/6). J Immunol 160:2393-400
Huffnagle, G B; Strieter, R M; McNeil, L K et al. (1997) Macrophage inflammatory protein-1alpha (MIP-1alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Cryptococcus neoformans infection. J Immunol 159:318-27
Huffnagle, G B; Toews, G B; Burdick, M D et al. (1996) Afferent phase production of TNF-alpha is required for the development of protective T cell immunity to Cryptococcus neoformans. J Immunol 157:4529-36