Abstract

. The risk of STD transmission between female sex partners is unclear. While bacterial STDs are uncommon, HPV is common and it occurs in association with cervical neoplasia. BV is common among women who have sex with women (WSW) and may constitute a STD in this group. The proposed research will define the epidemiology of HPV infection among WSW by defining the type-specific prevalence of HPV in relationship to sexual experience with both men and women, specific sexual practices and development of cervical neoplasia. It will also define the prevalence, and vaginal microbiology of BV and the relationships between BV and sexual history, sexual practices, and douching. It will address the issue of BV as a STD in monogamous female couples by performing a randomized trial of antimicrobial treatment of female partners of women with BV.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AI041153-02
Application #
2672972
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1997-07-01
Project End
2002-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Marrazzo, Jeanne M; Antonio, May; Agnew, Kathy et al. (2009) Distribution of genital Lactobacillus strains shared by female sex partners. J Infect Dis 199:680-3
Marrazzo, Jeanne M; Stine, Kathleen (2004) Reproductive health history of lesbians: implications for care. Am J Obstet Gynecol 190:1298-304
Marrazzo, Jeanne M; Stine, Kathleen; Wald, Anna (2003) Prevalence and risk factors for infection with herpes simplex virus type-1 and -2 among lesbians. Sex Transm Dis 30:890-5
Marrazzo, Jeanne M; Koutsky, Laura A; Eschenbach, David A et al. (2002) Characterization of vaginal flora and bacterial vaginosis in women who have sex with women. J Infect Dis 185:1307-13
Marrazzo, Jeanne M; Handsfield, H Hunter; Whittington, William L H (2002) Predicting chlamydial and gonococcal cervical infection: implications for management of cervicitis. Obstet Gynecol 100:579-84
Marrazzo, J M; Koutsky, L A; Kiviat, N B et al. (2001) Papanicolaou test screening and prevalence of genital human papillomavirus among women who have sex with women. Am J Public Health 91:947-52