Regulation of Substance P in Prolonged Nociception

Igwe, Orisa J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29AR041606-05
• Application #: 2080822
• Study Section: Neurological Sciences Subcommittee 1 (NLS)
• Project Start: 1991-09-01
• Project End: 1997-08-31
• Budget Start: 1995-09-01
• Budget End: 1997-08-31
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: University of Missouri Kansas City
• Department: Pharmacology
• Type: Schools of Pharmacy
• DUNS #: 800772162
• City: Kansas City
• State: MO
• Country: United States
• Zip Code: 64110

Publications

Igwe, O J; Chronwall, B M (2001) Hyperalgesia induced by peripheral inflammation is mediated by protein kinase C betaII isozyme in the rat spinal cord. Neuroscience 104:875-90

Igwe, O J; Murray, J N; Moolwaney, A S (2001) Interleukin 1-induced cyclooxygenase and nitric oxide synthase gene expression in the rat dorsal root ganglia is modulated by antioxidants. Neuroscience 105:971-85

Igwe, O J; Filla, M B (1997) Aging-related regulation of myo-inositol 1,4,5-trisphosphate signal transduction pathway in the rat striatum. Brain Res Mol Brain Res 46:39-53

Igwe, O J (1994) Modulation of substance P-ergic system in the rat spinal cord by an opioid antagonist. Brain Res Mol Brain Res 21:263-73

Igwe, O J; Ning, L (1994) Regulation of the second-messenger systems in the rat spinal cord during prolonged peripheral inflammation. Pain 58:63-75

Igwe, O J; Ning, L (1993) Inositol 1,4,5-trisphosphate arm of the phosphatidylinositide signal transduction pathway in the rat cerebellum during aging. Neurosci Lett 164:167-70

Igwe, O J (1993) Regulation of substance P receptor system in rat striatum by chronic naltrexone treatment. Brain Res Mol Brain Res 20:40-50