Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29AR042417-02
Application #
2081657
Study Section
Special Emphasis Panel (ZRG4-GMA-2 (01))
Project Start
1995-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Richardson, D W; Dodge, G R (2003) Dose-dependent effects of corticosteroids on the expression of matrix-related genes in normal and cytokine-treated articular chondrocytes. Inflamm Res 52:39-49
Estrada, L E; Dodge, G R; Richardson, D W et al. (2001) Characterization of a biomaterial with cartilage-like properties expressing type X collagen generated in vitro using neonatal porcine articular and growth plate chondrocytes. Osteoarthritis Cartilage 9:169-77
Richardson, D W; Dodge, G R (2000) Effects of interleukin-1beta and tumor necrosis factor-alpha on expression of matrix-related genes by cultured equine articular chondrocytes. Am J Vet Res 61:624-30
Fang, Q; Sun, Y Y; Cai, W et al. (2000) Cartilage-reactive T cells in rheumatoid synovium. Int Immunol 12:659-69
Dodge, G R; Diaz, A; Sanz-Rodriguez, C et al. (1998) Effects of interferon-gamma and tumor necrosis factor alpha on the expression of the genes encoding aggrecan, biglycan, and decorin core proteins in cultured human chondrocytes. Arthritis Rheum 41:274-83
Dodge, G R; Hawkins, D; Boesler, E et al. (1998) Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts. Osteoarthritis Cartilage 6:435-40
Richardson, D W; Dodge, G R (1998) Molecular characteristics of equine stromelysin and the tissue inhibitor of metalloproteinase 1. Am J Vet Res 59:1557-62
Jimenez, S A; Ala-Kokko, L; Prockop, D J et al. (1997) Characterization of human type II procollagen and collagen-specific antibodies and their application to the study of human type II collagen processing and ultrastructure. Matrix Biol 16:29-39
Richardson, D W; Dodge, G R (1997) Cloning of equine type II procollagen and the modulation of its expression in cultured equine articular chondrocytes. Matrix Biol 16:59-64