Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
7R29CA045327-06
Application #
3458359
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1988-07-01
Project End
1994-06-30
Budget Start
1993-05-19
Budget End
1994-06-30
Support Year
6
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Oishi, A J; Inoue, Y; Souba, W W et al. (1996) Alterations in carrier-mediated glutamine transport after a model of canine jejunal autotransplantation. Dig Dis Sci 41:1915-24
Bode, B P; Souba, W W (1994) Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. Ann Surg 220:411-22;discussion 422-4
Dudrick, P S; Souba, W W (1994) Cytokines, sepsis, and the surgeon: a perspective. Surg Annu 26:1-26
Espat, N J; Copeland, E M; Souba, W W (1994) Accelerated hepatic arginine transport in the tumor-bearing rat. Ann Surg Oncol 1:147-56
Sarantos, P; Abouhamze, A; Abcouwer, S et al. (1994) Cytokines decrease glutaminase expression in human fibroblasts. Surgery 116:276-83;discussion 283-4
Inoue, Y; Bode, B P; Souba, W W (1994) Antibody to tumor necrosis factor attenuates endotoxin-stimulated amino acid transport in rat liver. Surgery 116:356-65;discussion 365-6
Inoue, Y; Copeland, E M; Souba, W W (1994) Growth hormone enhances amino acid uptake by the human small intestine. Ann Surg 219:715-22;discussion 722-4
Watkins, K T; Copeland, E M; Souba, W W (1994) Induction of hepatic system y(+)-mediated L-arginine transport by prostaglandin E2. Am J Surg 167:128-33;discussion 133-4
Sarantos, P; Abouhamze, A; Chakrabarti, R et al. (1994) Glucocorticoids regulate intestinal glutamine synthetase gene expression in endotoxemia. Arch Surg 129:59-65
Watkins, K T; Dudrick, P S; Copeland, E M et al. (1994) Interleukin-6 and dexamethasone work coordinately to augment hepatic amino acid transport. J Trauma 36:523-8

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