Approximately 15% of lung cancer in women occurs among non- smokers. A case-control epidemiologic study is proposed to investigate factors associated with the development of lung cancer in these non-smoking women. Risk factors of particular interest to the study include exposure to sidestream smoke at home, at the worksite and elsewhere, exposure to indoor radon in current and previous Florida homes, occupational exposures to lung carcinogens and a family history of lung cancer. The study will collect data over a four year period from 300 or more cases of histologically confirmed carcinoma of the lung and 600 age and race matched controls living in an eleven county study area. A structured interview will be utilized to collect data on the risk factors of interest and possible confounding factors. For all participants who have resided in Florida for ten years or longer, measurements will be made of indoor radon levels in current and prior Florida homes. Two alpha track detectors will be placed in each eligible and consenting household for a twelve month period. The result of this study will provide important new information on the etiology of lung cancer among non-smoking women.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA045513-02
Application #
3458415
Study Section
Epidemiology and Disease Control Subcommittee 3 (EDC)
Project Start
1987-07-01
Project End
1992-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of South Florida
Department
Type
Schools of Public Health
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612
Candelora, E C; Stockwell, H G; Armstrong, A W et al. (1992) Dietary intake and risk of lung cancer in women who never smoked. Nutr Cancer 17:263-70
Stockwell, H G; Goldman, A L; Lyman, G H et al. (1992) Environmental tobacco smoke and lung cancer risk in nonsmoking women. J Natl Cancer Inst 84:1417-22