Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
3R29CA046677-05S1
Application #
3458700
Study Section
Virology Study Section (VR)
Project Start
1989-08-25
Project End
1994-07-31
Budget Start
1993-08-01
Budget End
1994-07-31
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Hunter College
Department
Type
Schools of Arts and Sciences
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10065
Saqcena, Mahesh; Menon, Deepak; Patel, Deven et al. (2013) Amino acids and mTOR mediate distinct metabolic checkpoints in mammalian G1 cell cycle. PLoS One 8:e74157
Foster, David A (2013) Phosphatidic acid and lipid-sensing by mTOR. Trends Endocrinol Metab 24:272-8
Yellen, Paige; Chatterjee, Amrita; Preda, Angela et al. (2013) Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-?-dependent G1 cell cycle arrest. Cancer Lett 333:239-43
Yellen, Paige; Saqcena, Mahesh; Salloum, Darin et al. (2011) High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1. Cell Cycle 10:3948-56
Toschi, Alfredo; Lee, Evan; Thompson, Sebastian et al. (2010) Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells. Cancer Lett 299:72-9
Foster, David A (2010) Reduced mortality and moderate alcohol consumption: the phospholipase D-mTOR connection. Cell Cycle 9:1291-4
Lyo, Donggon; Xu, Limei; Foster, David A (2010) Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway. Biochem Biophys Res Commun 396:562-5
Toschi, Alfredo; Lee, Evan; Xu, Limei et al. (2009) Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. Mol Cell Biol 29:1411-20
Foster, David A; Toschi, Alfredo (2009) Targeting mTOR with rapamycin: one dose does not fit all. Cell Cycle 8:1026-9
Foster, David A (2009) Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells. Biochim Biophys Acta 1791:949-55

Showing the most recent 10 out of 11 publications