It is known that women who are first degree relatives of breast cancer patients are at greater risk for developing breast cancer than other women in the same age group. The proposed study is targeted at this special group of high risk women, in an attempt to increase their utilization of screening mammography. A randomized pretest-posttest control group design will be used to evaluate the effectiveness of a targeted mail-out intervention, which will emphasize family history as a risk factor in breast cancer, the efficacy and importance of mammography, and the NCI age specific screening mammography guidelines for high risk women. Specifically, the study seeks to accomplish the following: 1. Use the California State Tumor Registry to obtain a statewide census of breast cancer cases. 2. Randomly sample the breast cancer cases to identify and seek permission to contact eligible female relatives. 3. Using the above procedure, obtain a sample of approximately 1500 women who are: first degree relatives of breast cancer patients, over the age of 40, and who themselves have never had breast cancer. 4. Contact these women in order to enroll them into the study, and collect baseline data on screening behaviors, as well as knowledge, attitudes and beliefs related to breast cancer and its early detection. 5. After randomization, implement the intervention in the experimental group. 6. Evaluate the effectiveness of the intervention in increasing rates of screening mammography and physician breast exam. 7. Evaluate the feasibility of adopting the intervention into the routine operations of local tumor registries.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA051142-05
Application #
2094146
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1990-05-03
Project End
1996-04-30
Budget Start
1994-05-01
Budget End
1996-04-30
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Organized Research Units
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Glenn, Beth A; Bastani, Roshan; Maxwell, Annette E (2013) The perils of ignoring design effects in experimental studies: lessons from a mammography screening trial. Psychol Health 28:593-602