Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA055536-05
Application #
2096669
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-02-01
Project End
1996-12-31
Budget Start
1996-02-01
Budget End
1996-12-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Brown, Andrew S; Mohanty, Bidyut K; Howe, Philip H (2015) Computational Identification of Post Translational Modification Regulated RNA Binding Protein Motifs. PLoS One 10:e0137696
Hussey, George S; Link, Laura A; Brown, Andrew S et al. (2012) Establishment of a TGF?-induced post-transcriptional EMT gene signature. PLoS One 7:e52624
Jiang, Yong; He, Xi; Howe, Philip H (2012) Disabled-2 (Dab2) inhibits Wnt/?-catenin signalling by binding LRP6 and promoting its internalization through clathrin. EMBO J 31:2336-49
Hussey, George S; Chaudhury, Arindam; Dawson, Andrea E et al. (2011) Identification of an mRNP complex regulating tumorigenesis at the translational elongation step. Mol Cell 41:419-31
Chaudhury, Arindam; Hussey, George S; Howe, Philip H (2011) 3'-UTR-mediated post-transcriptional regulation of cancer metastasis: beginning at the end. RNA Biol 8:595-9
Chaudhury, Arindam; Hussey, George S; Ray, Partho S et al. (2010) TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol 12:286-93
Chaudhury, Arindam; Chander, Praveen; Howe, Philip H (2010) Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles. RNA 16:1449-62
Jiang, Y; Luo, W; Howe, P H (2009) Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions. Oncogene 28:2999-3007
Chaudhury, Arindam; Howe, Philip H (2009) The tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma. IUBMB Life 61:929-39
Ramesh, Sneha; Wildey, Gary M; Howe, Philip H (2009) Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim. Cell Cycle 8:11-7

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