Regulation of Expression of the P53 Tumor Suppressor

Reisman, David J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 5R29CA059986-03
• Application #: 2100596
• Study Section: Pathology B Study Section (PTHB)
• Project Start: 1994-02-01
• Project End: 1999-01-31
• Budget Start: 1996-02-01
• Budget End: 1997-01-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of South Carolina at Columbia
• Department: Biology
• Type: Schools of Arts and Sciences
• DUNS #: 111310249
• City: Columbia
• State: SC
• Country: United States
• Zip Code: 29208

Publications

Roy, B; Reisman, D (1996) Positive and negative regulatory elements in the murine p53 promoter. Oncogene 13:2359-66

Balint, E; Reisman, D (1996) Increased rate of transcription contributes to elevated expression of the mutant p53 gene in Burkitt's lymphoma cells. Cancer Res 56:1648-53

Reisman, D; Balint e; Loging, W T et al. (1996) A novel transcript encoded within the 10-kb first intron of the human p53 tumor suppressor gene (D17S2179E) is induced during differentiation of myeloid leukemia cells. Genomics 38:364-70

Uittenbogaard, M N; Giebler, H A; Reisman, D et al. (1995) Transcriptional repression of p53 by human T-cell leukemia virus type I Tax protein. J Biol Chem 270:28503-6

Roy, B; Beamon, J; Balint, E et al. (1994) Transactivation of the human p53 tumor suppressor gene by c-Myc/Max contributes to elevated mutant p53 expression in some tumors. Mol Cell Biol 14:7805-15