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Salti, G I; Kichina, J V; Das Gupta, T K et al. (2001) Betulinic acid reduces ultraviolet-C-induced DNA breakage in congenital melanocytic naeval cells: evidence for a potential role as a chemopreventive agent. Melanoma Res 11:99-104
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Salti, G I; Das Gupta, T K; Constantinou, A I (2000) A novel use for the comet assay: detection of topoisomerase II inhibitors. Anticancer Res 20:3189-93
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Salti, G I; Grewal, S; Mehta, R R et al. (2000) Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells. Eur J Cancer 36:796-802
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Constantinou, A I; Kamath, N; Murley, J S (1998) Genistein inactivates bcl-2, delays the G2/M phase of the cell cycle, and induces apoptosis of human breast adenocarcinoma MCF-7 cells. Eur J Cancer 34:1927-34
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Boddie Jr, A W; Constantinou, A; Williams, C et al. (1998) Nitrogen mustard up-regulates Bcl-2 and GSH and increases NTP and PCr in HT-29 colon cancer cells. Br J Cancer 77:1395-404
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Constantinou, A I; Krygier, A E; Mehta, R R (1998) Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice. Am J Clin Nutr 68:1426S-1430S
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Khodarev, N N; Narayana, A; Constantinou, A et al. (1997) Topologically constrained domains of supercoiled DNA in eukaryotic cells. DNA Cell Biol 16:1051-8
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Murley, J S; Constantinou, A; Kamath, N S et al. (1997) WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells. Cell Prolif 30:283-94
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Moon, R C; Constantinou, A I (1997) Dietary retinoids and carotenoids in rodent models of mammary tumorigenesis. Breast Cancer Res Treat 46:181-9
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Ganapathi, R; Constantinou, A; Kamath, N et al. (1996) Resistance to etoposide in human leukemia HL-60 cells: reduction in drug-induced DNA cleavage associated with hypophosphorylation of topoisomerase II phosphopeptides. Mol Pharmacol 50:243-8
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