Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA064225-03
Application #
2106566
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1994-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Sivaraman, Lakshmi; Medina, Daniel (2002) Hormone-induced protection against breast cancer. J Mammary Gland Biol Neoplasia 7:77-92
Sivaraman, Lakshmi; Gay, Jason; Hilsenbeck, Susan G et al. (2002) Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast Cancer Res Treat 73:75-83
Sivaraman, L; Conneely, O M; Medina, D et al. (2001) p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A 98:12379-84
Sivaraman, L; Hilsenbeck, S G; Zhong, L et al. (2001) Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. J Endocrinol 171:75-83
Sivaraman, L; Nawaz, Z; Medina, D et al. (2000) The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis. Breast Cancer Res Treat 62:185-95
Sivaraman, L; Stephens, L C; Markaverich, B M et al. (1998) Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis 19:1573-81
Humphreys, R C; Lydon, J; O'Malley, B W et al. (1997) Mammary gland development is mediated by both stromal and epithelial progesterone receptors. Mol Endocrinol 11:801-11