Receptor Tyrosine Phosphatase Rptp Alpha

Sap, Jan M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 1R29CA068365-01A1
• Application #: 2112308
• Study Section: Medical Biochemistry Study Section (MEDB)
• Project Start: 1996-04-21
• Project End: 2001-03-31
• Budget Start: 1996-04-21
• Budget End: 1997-03-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: New York University
• Department: Pharmacology
• Type: Schools of Medicine
• City: New York
• State: NY
• Country: United States
• Zip Code: 10016

Publications

Ardini, E; Agresti, R; Tagliabue, E et al. (2000) Expression of protein tyrosine phosphatase alpha (RPTPalpha) in human breast cancer correlates with low tumor grade, and inhibits tumor cell growth in vitro and in vivo. Oncogene 19:4979-87

Shen, P; Canoll, P D; Sap, J et al. (1999) Expression of a truncated receptor protein tyrosine phosphatase kappa in the brain of an adult transgenic mouse. Brain Res 826:157-71

Su, J; Muranjan, M; Sap, J (1999) Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts. Curr Biol 9:505-11

Jacob, K K; Sap, J; Stanley, F M (1998) Receptor-like protein-tyrosine phosphatase alpha specifically inhibits insulin-increased prolactin gene expression. J Biol Chem 273:4800-9

Su, J; Yang, L T; Sap, J (1996) Association between receptor protein-tyrosine phosphatase RPTPalpha and the Grb2 adaptor. Dual Src homology (SH) 2/SH3 domain requirement and functional consequences. J Biol Chem 271:28086-96