Mechanisms for Ebv EBNA-2 Immortalizing Function

Ling, Paul Dalling

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: First Independent Research Support & Transition (FIRST) Awards (R29)
• Project #: 1R29CA069437-01
• Application #: 2113506
• Study Section: Virology Study Section (VR)
• Project Start: 1996-03-15
• Project End: 2001-02-28
• Budget Start: 1996-03-15
• Budget End: 1997-02-28
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Baylor College of Medicine
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 074615394
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77030

Publications

Peng, R; Tan, J; Ling, P D (2000) Conserved regions in the Epstein-Barr virus leader protein define distinct domains required for nuclear localization and transcriptional cooperation with EBNA2. J Virol 74:9953-63

Peng, R; Gordadze, A V; Fuentes Panana, E M et al. (2000) Sequence and functional analysis of EBNA-LP and EBNA2 proteins from nonhuman primate lymphocryptoviruses. J Virol 74:379-89

Fuentes-Panana, E M; Peng, R; Brewer, G et al. (2000) Regulation of the Epstein-Barr virus C promoter by AUF1 and the cyclic AMP/protein kinase A signaling pathway. J Virol 74:8166-75

Fuentes-Panana, E M; Swaminathan, S; Ling, P D (1999) Transcriptional activation signals found in the Epstein-Barr virus (EBV) latency C promoter are conserved in the latency C promoter sequences from baboon and Rhesus monkey EBV-like lymphocryptoviruses (cercopithicine herpesviruses 12 and 15). J Virol 73:826-33

Fuentes-Panana, E M; Ling, P D (1998) Characterization of the CBF2 binding site within the Epstein-Barr virus latency C promoter and its role in modulating EBNA2-mediated transactivation. J Virol 72:693-700